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fliD flagellar filament capping protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946428, updated on 6-Jul-2026
Official Symbol
fliD
Official Full Name
flagellar filament capping protein
Primary source
ECOCYC:EG10841
Locus tag
b1924
See related
ASAP:ABE-0006407
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1923; flbC; rfs
Summary
Flagellar regulon. [More information is available at EcoGene: EG10841]. The filament cap lies at the distal, growing end of the flagellar filament and plays a critical role in the assembly of flagellin (FliC) monomers into the growing filament . [More information is available at EcoCyc: EG10841].
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Sequence:
NC_000913.3 (2003872..2005278)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene flagellar filament structural protein Neighboring gene flagellar biosynthesis protein FliS Neighboring gene flagellar biosynthesis protein FliT

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Excretion of unassembled flagellin by Salmonella typhimurium mutants deficient in hook-associated proteins. Homma M, et al. J Bacteriol, 1984 Sep. PMID 6384179, Free PMC Article
  2. Self-Oligomerizing Structure of the Flagellar Cap Protein FliD and Its Implication in Filament Assembly. Song WS, et al. J Mol Biol, 2017 Mar 24. PMID 28179186
  3. Isolation and characterization of Escherichia coli hag operator mutants whose hag48 expression has become repressible by a Salmonella H1 repressor. Hanafusa T, et al. Mol Gen Genet, 1989 Mar. PMID 2659972
  4. DNA sequence adjacent to flagellar genes and evolution of flagellar-phase variation. Szekely E, et al. J Bacteriol, 1983 Jul. PMID 6305924, Free PMC Article
  5. Molecular Determinants of Filament Capping Proteins Required for the Formation of Functional Flagella in Gram-Negative Bacteria. Nedeljković M, et al. Biomolecules, 2021 Sep 22. PMID 34680030, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Molecular Determinants of Filament Capping Proteins Required for the Formation of Functional Flagella in Gram-Negative Bacteria.
    Title: Molecular Determinants of Filament Capping Proteins Required for the Formation of Functional Flagella in Gram-Negative Bacteria.
  2. Escherichia coli FliD consists of three domains (D1, D2, and D3) and forms a hexamer plate of the D2 and D3 domains that resembles a six-pointed star with legs consisting of the D1 domain. In contrast, the D2 and D3 domains of Salmonella typhimurium FliD assemble into a pentamer as a five-pointed star plate. Despite their distinct oligomeric states, ecFliD and stFliD engage a common molecular surface for oligomerization.
    Title: Self-Oligomerizing Structure of the Flagellar Cap Protein FliD and Its Implication in Filament Assembly.
  3. analysis of integration and expression at four candidate loci, fliD, fliS, fliT, and fliY, of the E. coli flagellar region 3a
    Title: Escherichia coli flagellar genes as target sites for integration and expression of genetic circuits.
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Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in bacterial-type flagellum-dependent cell motility IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within bacterial-type flagellum-dependent cell motility IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in bacterial-type flagellum IEA
Inferred from Electronic Annotation
more info
  
is_active_in bacterial-type flagellum filament cap IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in bacterial-type flagellum filament cap IEA
Inferred from Electronic Annotation
more info
  
located_in bacterial-type flagellum hook IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
flagellar filament capping protein

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2003872..2005278
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416434.1 flagellar filament capping protein

    See identical proteins and their annotated locations for NP_416434.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    B9VS64
    Conserved Domains (1) summary
    PRK08032
    Location:1 → 462
    fliD; flagellar capping protein; Reviewed
Nucleotide Protein
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