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edd phosphogluconate dehydratase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946362, updated on 19-Sep-2024

Summary

Official Symbol
edd
Official Full Name
phosphogluconate dehydratase
Primary source
ECOCYC:EG10257
Locus tag
b1851
See related
ASAP:ABE-0006166
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1852
Summary
There has been little work done on this enzyme in Escherichia coli. [More information is available at EcoCyc: EG10257].
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Genomic context

Sequence:
NC_000913.3 (1932793..1934604, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene phosphoribosylglycinamide formyltransferase 2 Neighboring gene KHG/KDPG aldolase Neighboring gene NADP(+)-dependent glucose-6-phosphate dehydrogenase Neighboring gene DNA-binding transcriptional repressor YebK

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables hydro-lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphogluconate dehydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables phosphogluconate dehydratase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables phosphogluconate dehydratase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphogluconate dehydratase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in D-gluconate catabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within D-gluconate catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in D-gluconate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in Entner-Doudoroff pathway through 6-phosphogluconate IEA
Inferred from Electronic Annotation
more info
 
involved_in carboxylic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
phosphogluconate dehydratase
NP_416365.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1932793..1934604 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416365.1 phosphogluconate dehydratase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416365.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A403CSJ0, A0A8S7CKQ8
    Conserved Domains (1) summary
    PRK09054
    Location:1603
    PRK09054; phosphogluconate dehydratase; Validated