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pphA phosphoprotein phosphatase 1 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946356, updated on 22-Aug-2021

Summary

Gene symbol
pphA
Gene description
phosphoprotein phosphatase 1
Primary source
ASAP:ABE-0006114
Locus tag
b1838
See related
ECOCYC:G7011
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1837; prpA; yebX
Summary
PrpA and PrpB are phosphatases that act in transduction of the misfolded protein stress signal in a pathway that includes the CpxR-CpxA two-component system and which activates transcription of the htrA gene . [More information is available at EcoCyc: G7011].
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Genomic context

Sequence:
NC_000913.3 (1922313..1922969, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF1480 domain-containing protein YebV Neighboring gene DUF1482 domain-containing protein YebW Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DUF2511 domain-containing protein YebY

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein tyrosine/serine/threonine phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to temperature stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
phosphoprotein phosphatase 1
NP_416352.4

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1922313..1922969 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416352.4 phosphoprotein phosphatase 1 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416352.4

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P55798
    Conserved Domains (1) summary
    PRK11439
    Location:1218
    pphA; protein-serine/threonine phosphatase
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