U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

mgrB PhoQ kinase inhibitor [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946351, updated on 26-Mar-2025
Official Symbol
mgrB
Official Full Name
PhoQ kinase inhibitor
Primary source
ECOCYC:G7002
Locus tag
b1826
See related
ASAP:ABE-0006078
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1824; yobG
Summary
Mg(2+) stimulon-PhoPQ regulon. [More information is available at EcoGene: EG14383]. Transcription of mgrB is induced by low magnesium and is controlled by the PhoP/PhoQ two-component system . [More information is available at EcoCyc: G7002].
NEW
Try the new Gene table
Try the new Transcript table
Sequence:
NC_000913.3 (1908623..1908766, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF2527 domain-containing protein YobF Neighboring gene uncharacterized protein YebO Neighboring gene uncharacterized protein YobH Neighboring gene DNA-binding transcriptional repressor KdgR

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Perturbation of the oxidizing environment of the periplasm stimulates the PhoQ/PhoP system in Escherichia coli. Lippa AM, et al. J Bacteriol, 2012 Mar. PMID 22267510, Free PMC Article
  2. Isolation and molecular characterization of the locked-on mutant of Mg2+ sensor PhoQ in Escherichia coli. Minagawa S, et al. Biosci Biotechnol Biochem, 2005 Jul. PMID 16041131
  3. MgrB affects the acid stress response of Escherichia coli by modulating the expression of iraM. Xu J, et al. FEMS Microbiol Lett, 2019 Jun 1. PMID 31158277
  4. Identification and molecular characterization of the Mg2+ stimulon of Escherichia coli. Minagawa S, et al. J Bacteriol, 2003 Jul. PMID 12813061, Free PMC Article
  5. Signal transduction cascade between EvgA/EvgS and PhoP/PhoQ two-component systems of Escherichia coli. Eguchi Y, et al. J Bacteriol, 2004 May. PMID 15126461, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. data suggest that MgrB affects the acid resistance of E. coli by modulating the expression of iraM, but not completely through PhoP/Q.
    Title: MgrB affects the acid stress response of Escherichia coli by modulating the expression of iraM.
Submit: New GeneRIF Correction

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to magnesium ion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of phosphorelay signal transduction system IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of phosphorelay signal transduction system IEA
Inferred from Electronic Annotation
more info
  
involved_in response to acidic pH IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
PhoQ kinase inhibitor

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1908623..1908766 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416340.1 PhoQ kinase inhibitor [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416340.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6G9RWA9
    Conserved Domains (1) summary
    PRK10299
    Location:1 → 47
    PRK10299; PhoP/PhoQ regulator MgrB
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.