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manY mannose-specific PTS enzyme IIC component [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946332, updated on 4-Feb-2026
Official Symbol
manY
Official Full Name
mannose-specific PTS enzyme IIC component
Primary source
ECOCYC:EG10568
Locus tag
b1818
See related
ASAP:ABE-0006056
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1816; pel; ptsP; ptsX
Summary
HT_Cmplx16_Mem: [More information is available at EcoGene: EG10568]. [More information is available at EcoCyc: EG10568].
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Sequence:
NC_000913.3 (1903082..1903882)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene TerC family inner membrane protein YoaE Neighboring gene protein YoaL Neighboring gene mannose-specific PTS enzyme IIAB component Neighboring gene mannose-specific PTS enzyme IID component Neighboring gene DUF986 domain-containing inner membrane protein YobD

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Bacteriophage infection is targeted to cellular poles. Edgar R, et al. Mol Microbiol, 2008 Jun. PMID 18363799, Free PMC Article
  2. Substrate-induced conformational changes in the membrane-embedded IIC(mtl)-domain of the mannitol permease from Escherichia coli, EnzymeII(mtl), probed by tryptophan phosphorescence spectroscopy. Veldhuis G, et al. J Biol Chem, 2005 Oct 21. PMID 16093245
  3. Increase of organic solvent tolerance by overexpression of manXYZ in Escherichia coli. Okochi M, et al. Appl Microbiol Biotechnol, 2007 Jan. PMID 17053901
  4. Gene fusions to the ptsM/pel locus of Escherichia coli. Palva ET, et al. Mol Gen Genet, 1985. PMID 3162078
  5. The role of phosphotransferase-mediated syntheses of fructose 1-phosphate and fructose 6-phosphate in the growth of Escherichia coli on fructose. Ferenci T, et al. Proc R Soc Lond B Biol Sci, 1974 Sep 17. PMID 4153999

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within D-glucose import across plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within N-acetylglucosamine transport EXP
Inferred from Experiment
more info
 PubMed 
acts_upstream_of_or_within fructose import across plasma membrane EXP
Inferred from Experiment
more info
 PubMed 
acts_upstream_of_or_within mannose transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in mannose transmembrane transport NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane HDA PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
mannose-specific PTS enzyme IIC component
NP_416332.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1903082..1903882
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416332.1 mannose-specific PTS enzyme IIC component

    See identical proteins and their annotated locations for NP_416332.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8S0FSV3
    Conserved Domains (1) summary
    PRK15065
    Location:1 → 263
    PRK15065; mannose/fructose/sorbose family PTS transporter subunit IIC
Nucleotide Protein
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