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fadD long-chain-fatty-acid--CoA ligase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946327, updated on 9-Mar-2022

Summary

Gene symbol
fadD
Gene description
long-chain-fatty-acid--CoA ligase
Primary source
ASAP:ABE-0006005
Locus tag
b1805
See related
ECOCYC:EG11530
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1803; oldD
Summary
The FadD protein, encoding fatty acyl-CoA synthetase, can transport long chain fatty acids across the inner membrane in an in vitro system . [More information is available at EcoCyc: EG11530].
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Genomic context

Sequence:
NC_000913.3 (1888061..1889746, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene carnitine monooxygenase subunit YeaX Neighboring gene RNase D Neighboring gene Slp family lipoprotein YeaY Neighboring gene N(6)-L-threonylcarbamoyladenine synthase, TsaB subunit

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables decanoate-CoA ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables fatty acid binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables long-chain fatty acid-CoA ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables long-chain fatty acid-CoA ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables long-chain fatty acid-CoA ligase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables oleic acid binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasmic side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasmic side of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
long-chain-fatty-acid--CoA ligase
NP_416319.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1888061..1889746 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416319.1 long-chain-fatty-acid--CoA ligase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416319.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P69451
    Conserved Domains (1) summary
    PRK08974
    Location:1560
    PRK08974; long-chain-fatty-acid--CoA ligase FadD