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ldhA D-lactate dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946315, updated on 6-May-2021

Summary

Gene symbol
ldhA
Gene description
D-lactate dehydrogenase
Primary source
ASAP:ABE-0004619
Locus tag
b1380
See related
ECOCYC:G592
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1377; hslF; hslI; htpH
Summary
There are three lactate dehydrogenase enzymes in Escherichia coli which interconvert pyruvate and lactate. [More information is available at EcoCyc: G592].
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Genomic context

Sequence:
NC_000913.3 (1441854..1442843, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative pyruvate-flavodoxin oxidoreductase Neighboring gene DUF333 domain-containing protein YdbJ Neighboring gene lipoprotein implicated in Novobiocin resistance Neighboring gene PF11739 family protein YdbH Neighboring gene lipoprotein YnbE Neighboring gene DUF1318 domain-containing protein YdbL

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables D-lactate dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables D-lactate dehydrogenase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables D-lactate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 
enables NAD binding IEA
Inferred from Electronic Annotation
more info
 
enables NADH binding IDA
Inferred from Direct Assay
more info
PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
D-lactate dehydrogenase
NP_415898.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1441854..1442843 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415898.1 D-lactate dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415898.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P52643
    Conserved Domains (1) summary
    cd12183
    Location:1328
    LDH_like_2; D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains
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