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nimT 2-nitroimidazole exporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946309, updated on 17-Dec-2024

Summary

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Official Symbol
nimT
Official Full Name
2-nitroimidazole exporter
Primary source
ECOCYC:G6977
Locus tag
b1791
See related
ASAP:ABE-0005962
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1789; yeaN
Summary
Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG13500]. The YeaN protein is an uncharacterised member of the major facilitator superfamily (MFS) of transporters . [More information is available at EcoCyc: G6977].
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Genomic context

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Sequence:
NC_000913.3 (1875673..1876854)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YoaI Neighboring gene DUF441 domain-containing inner membrane protein YeaL Neighboring gene DNA-binding transcriptional repressor NimR Neighboring gene DUF488 domain-containing protein YeaO Neighboring gene DUF333 domain-containing lipoprotein YoaF

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of pathogen-specific and conserved genes expressed in vivo by an avian pathogenic Escherichia coli strain. Dozois CM, et al. Proc Natl Acad Sci U S A, 2003 Jan 7. PMID 12506201, Free PMC Article
  2. Role of transcription factor NimR (YeaM) in sensitivity control of Escherichia coli to 2-nitroimidazole. Ogasawara H, et al. FEMS Microbiol Lett, 2015 Jan. PMID 25790494
  3. Microbial drug efflux proteins of the major facilitator superfamily. Saidijam M, et al. Curr Drug Targets, 2006 Jul. PMID 16842212
  4. The major facilitator superfamily. Saier MH Jr, et al. J Mol Microbiol Biotechnol, 1999 Nov. PMID 10943556
  5. A 460-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 40.1-50.0 min region on the linkage map. Itoh T, et al. DNA Res, 1996 Dec 31. PMID 9097040

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Process Evidence Code Pubs
involved_in response to antibiotic IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to antibiotic IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within transmembrane transport RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
2-nitroimidazole exporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1875673..1876854
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416305.1 2-nitroimidazole exporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416305.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8H9T0N9, A0A8T5Y8J3
    Conserved Domains (1) summary
    cd17409
    Location:16 → 388
    MFS_NIMT_like; 2-nitroimidazole transporter and similar proteins of the Major Facilitator Superfamily of transporters
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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