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thiB thiamine ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946306, updated on 6-May-2021

Summary

Gene symbol
thiB
Gene description
thiamine ABC transporter periplasmic binding protein
Primary source
ASAP:ABE-0000249
Locus tag
b0068
See related
ECOCYC:EG11574
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0069; sfuA; tbpA; yabL
Summary
thiBPQ operon expression is controlled by a thiamine pyrophosphate (TPP) responsive riboswitch in the 128 nt 5' UTR. [More information is available at EcoGene: EG11574]. The Escherichia coli SufA/TbpA protein has been purified and characterized as a 34.2 kDa monomer. [More information is available at EcoCyc: EG11574].
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Genomic context

Sequence:
NC_000913.3 (74497..75480, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DedA family protein YabI Neighboring gene thiamine ABC transporter ATP binding subunit Neighboring gene thiamine ABC transporter membrane subunit Neighboring gene ncRNA Neighboring gene DNA-binding transcriptional dual regulator SgrR

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables thiamine binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables thiamine binding IEA
Inferred from Electronic Annotation
more info
 
enables thiamine binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables thiamine pyrophosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables thiamine pyrophosphate binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in thiamine transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within thiamine transport IDA
Inferred from Direct Assay
more info
PubMed 
acts_upstream_of_or_within thiamine transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 
located_in outer membrane-bounded periplasmic space IEA
Inferred from Electronic Annotation
more info
 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
thiamine ABC transporter periplasmic binding protein
NP_414610.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    74497..75480 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414610.1 thiamine ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414610.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P31550
    Conserved Domains (1) summary
    PRK11205
    Location:13327
    tbpA; thiamine transporter substrate binding subunit; Provisional
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