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yeaG protein kinase YeaG [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946297, updated on 23-Apr-2026
Official Symbol
yeaG
Official Full Name
protein kinase YeaG
Primary source
ECOCYC:G6969
Locus tag
b1783
See related
ASAP:ABE-0005935
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1781
Summary
AFMB Structural Genomics target Number 55 (http://afmb.cnrs-mrs.fr/article171.html). [More information is available at EcoGene: EG13493]. YeaG is a member of the PrkA family of serine protein kinases. [More information is available at EcoCyc: G6969].
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Sequence:
NC_000913.3 (1866908..1868842)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene methylglyoxal reductase YeaE Neighboring gene MltA-interacting protein Neighboring gene DUF444 domain-containing protein YeaH Neighboring gene putative c-di-GMP binding protein CdgI

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Phosphoproteome Study of Escherichia coli Devoid of Ser/Thr Kinase YeaG During the Metabolic Shift From Glucose to Malate. Sultan A, et al. Front Microbiol, 2021. PMID 33889145, Free PMC Article
  2. A novel regulatory factor affecting the transcription of methionine biosynthesis genes in Escherichia coli experiencing sustained nitrogen starvation. Switzer A, et al. Microbiology (Reading), 2018 Nov. PMID 29957170
  3. EcID. A database for the inference of functional interactions in E. coli. Andres Leon E, et al. Nucleic Acids Res, 2009 Jan. PMID 19004873, Free PMC Article
  4. Identification of RpoS (sigma(S))-regulated genes in Salmonella enterica serovar typhimurium. Ibanez-Ruiz M, et al. J Bacteriol, 2000 Oct. PMID 11004173, Free PMC Article
  5. Genome-wide analysis of the general stress response network in Escherichia coli: sigmaS-dependent genes, promoters, and sigma factor selectivity. Weber H, et al. J Bacteriol, 2005 Mar. PMID 15716429, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. this study identifies YeaG as a novel regulatory factor in E. coli affecting the transcription of methionine biosynthesis genes under sustained N starvation.
    Title: A novel regulatory factor affecting the transcription of methionine biosynthesis genes in Escherichia coli experiencing sustained nitrogen starvation.
  2. results indicate that yeaG is required to fully execute the rpoS-dependent gene expression program to allow E. coli to adapt to sustained N starvation and unravels a novel facet to the regulatory basis that underpins adaptive response to N stress.
    Title: Adaptation to sustained nitrogen starvation by Escherichia coli requires the eukaryote-like serine/threonine kinase YeaG.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein kinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to nitrogen starvation IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within cellular response to nitrogen starvation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within protein autophosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within protein phosphorylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
protein kinase YeaG
NP_416297.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1866908..1868842
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416297.1 protein kinase YeaG

    See identical proteins and their annotated locations for NP_416297.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A2X1NJ11
    Conserved Domains (1) summary
    PRK15455
    Location:1 → 644
    PRK15455; PrkA family serine protein kinase; Provisional
Nucleotide Protein
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