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puuP putrescine:H(+) symporter PuuP [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946287, updated on 30-Jul-2025
Official Symbol
puuP
Official Full Name
putrescine:H(+) symporter PuuP
Primary source
ECOCYC:G6643
Locus tag
b1296
See related
ASAP:ABE-0004362
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1291; ycjJ
Summary
PuuP is a putrescine importer. [More information is available at EcoCyc: G6643].
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Sequence:
NC_000913.3 (1357802..1359187, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putrescine ABC exporter membrane subunit SapB Neighboring gene putative periplasmic binding protein SapA Neighboring gene DUF2543 domain-containing protein YmjA Neighboring gene protein YmjE Neighboring gene glutamate-putrescine ligase Neighboring gene gamma-glutamyl-gamma-aminobutyrate hydrolase

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The putrescine Importer PuuP of Escherichia coli K-12. Kurihara S, et al. J Bacteriol, 2009 Apr. PMID 19181795, Free PMC Article
  2. Over 1000 genes are involved in the DNA damage response of Escherichia coli. Khil PP, et al. Mol Microbiol, 2002 Apr. PMID 11967071
  3. Experimentally constrained topology models for 51,208 bacterial inner membrane proteins. Granseth E, et al. J Mol Biol, 2005 Sep 23. PMID 16120447
  4. A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12. Kurihara S, et al. J Biol Chem, 2005 Feb 11. PMID 15590624
  5. Global topology analysis of the Escherichia coli inner membrane proteome. Daley DO, et al. Science, 2005 May 27. PMID 15919996

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables putrescine transmembrane transporter activity EXP
Inferred from Experiment
more info
 PubMed 
enables putrescine transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables solute:proton symporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables solute:proton symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in putrescine catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within putrescine catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within putrescine transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
putrescine:H(+) symporter PuuP

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1357802..1359187 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415812.4 putrescine:H(+) symporter PuuP

    See identical proteins and their annotated locations for NP_415812.4

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A376K0W2
    Conserved Domains (1) summary
    COG0531
    Location:18 → 450
    PotE; Amino acid transporter [Amino acid transport and metabolism]
Nucleotide Protein
Heading Accession and Version

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