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astC succinylornithine transaminase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946255, updated on 4-Feb-2026
Official Symbol
astC
Official Full Name
succinylornithine transaminase
Primary source
ECOCYC:G6944
Locus tag
b1748
See related
ASAP:ABE-0005824
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
argM; cstC; ECK1746; ydjW
Summary
The astC gene product is 60% identical to the argD gene product. [More information is available at EcoCyc: G6944].
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Sequence:
NC_000913.3 (1830762..1831982, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene succinylglutamate desuccinylase Neighboring gene N-succinylarginine dihydrolase Neighboring gene aldehyde dehydrogenase Neighboring gene arginine N-succinyltransferase Neighboring gene exodeoxyribonuclease III Neighboring gene DedA family protein YdjX

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Biosynthesis and metabolism of arginine in bacteria. Cunin R, et al. Microbiol Rev, 1986 Sep. PMID 3534538, Free PMC Article
  2. Phenotype microarrays for high-throughput phenotypic testing and assay of gene function. Bochner BR, et al. Genome Res, 2001 Jul. PMID 11435407, Free PMC Article
  3. The SWISS-PROT protein sequence data bank, recent developments. Bairoch A, et al. Nucleic Acids Res, 1993 Jul 1. PMID 8332529, Free PMC Article
  4. Effects of mutations in the rpoS gene on cell viability and global gene expression under nitrogen starvation in Escherichia coli. Kabir MS, et al. Microbiology (Reading), 2004 Aug. PMID 15289551
  5. The Escherichia coli starvation gene cstC is involved in amino acid catabolism. Fraley CD, et al. J Bacteriol, 1998 Aug. PMID 9696780, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
  
enables succinylornithine transaminase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables succinylornithine transaminase activity IEA
Inferred from Electronic Annotation
more info
  
enables transaminase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-arginine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-arginine biosynthetic process via ornithine IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within L-arginine biosynthetic process via ornithine IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in L-arginine catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-arginine catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within L-arginine catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in L-ornithine catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within L-ornithine catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in amino acid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in arginine metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
succinylornithine transaminase
NP_416262.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1830762..1831982 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416262.1 succinylornithine transaminase

    See identical proteins and their annotated locations for NP_416262.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A376K044, A0A8S7HY38
    Conserved Domains (1) summary
    PRK12381
    Location:1 → 406
    PRK12381; bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional
Nucleotide Protein
Heading Accession and Version

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