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metC cystathionine beta-lyase/L-cysteine desulfhydrase/alanine racemase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946240, updated on 6-May-2021

Summary

Gene symbol
metC
Gene description
cystathionine beta-lyase/L-cysteine desulfhydrase/alanine racemase
Primary source
ASAP:ABE-0009878
Locus tag
b3008
See related
ECOCYC:EG10583
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3000
Summary
The Flint et al. [More information is available at EcoGene: EG10583]. Several distinct proteins exhibit cysteine desulfhydrase activity, which is involved in cysteine degradation . [More information is available at EcoCyc: EG10583].
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Genomic context

Sequence:
NC_000913.3 (3152236..3153423)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene Ton complex subunit ExbD Neighboring gene Ton complex subunit ExbB Neighboring gene DedA family protein YghB Neighboring gene DNA-binding transcriptional activator YqhC

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables L-cysteine desulfhydrase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables L-cysteine desulfhydrase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables alanine racemase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables cystathionine beta-lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables cystathionine beta-lyase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables cystathionine beta-lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables cysteine-S-conjugate beta-lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables identical protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables pyridoxal phosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cystathionine beta-lyase/L-cysteine desulfhydrase/alanine racemase
NP_417481.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3152236..3153423
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417481.1 cystathionine beta-lyase/L-cysteine desulfhydrase/alanine racemase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417481.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P06721
    Conserved Domains (1) summary
    PRK08114
    Location:1395
    PRK08114; cystathionine beta-lyase; Provisional
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