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fadK short chain acyl-CoA synthetase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946213, updated on 9-Mar-2022

Summary

Gene symbol
fadK
Gene description
short chain acyl-CoA synthetase
Primary source
ASAP:ABE-0005676
Locus tag
b1701
See related
ECOCYC:EG12357
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1699; ydiD
Summary
AFMB Structural Genomics target Number 54 (http://afmb.cnrs-mrs.fr/article171.html). [More information is available at EcoGene: EG12357]. FadK is an acyl-CoA synthetase that is primarily active on short chain fatty acids and acts in anaerobic -oxidation of fatty acids . [More information is available at EcoCyc: EG12357].
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Genomic context

Sequence:
NC_000913.3 (1782977..1784677)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative electron transfer flavoprotein subunit YdiR Neighboring gene putative electron transfer flavoprotein-quinone oxidoreductase YdiS Neighboring gene ferredoxin-like protein YdiT Neighboring gene phosphoenolpyruvate synthetase Neighboring gene phosphoenolpyruvate synthetase regulatory protein

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables medium-chain fatty acid-CoA ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in fatty acid beta-oxidation IEA
Inferred from Electronic Annotation
more info
 
involved_in fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within fatty acid oxidation IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
short chain acyl-CoA synthetase
NP_416216.5

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1782977..1784677
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416216.5 short chain acyl-CoA synthetase [Escherichia coli str. K-12 substr. MG1655]

    Status: PROVISIONAL

    Conserved Domains (1) summary
    PRK06087
    Location:20566
    PRK06087; medium-chain fatty-acid--CoA ligase