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gloA glyoxalase I [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946161, updated on 6-May-2021

Summary

Gene symbol
gloA
Gene description
glyoxalase I
Primary source
ASAP:ABE-0005520
Locus tag
b1651
See related
ECOCYC:G6891
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1647
Summary
Glyoxalase I catalyzes the first of two sequential steps in the conversion of methylgloxal to D-lactate. [More information is available at EcoCyc: G6891].
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Genomic context

Sequence:
NC_000913.3 (1727837..1728244)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional repressor NemR Neighboring gene N-ethylmaleimide reductase Neighboring gene RNase T Neighboring gene putative ATP-dependent helicase Lhr

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables lactoylglutathione lyase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables lactoylglutathione lyase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables lactoylglutathione lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nickel cation binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1727837..1728244
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416168.1 glyoxalase I [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416168.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0AC81
    Conserved Domains (1) summary
    TIGR00068
    Location:2135
    glyox_I; lactoylglutathione lyase
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