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murC UDP-N-acetylmuramate--L-alanine ligase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946153, updated on 19-Sep-2024

Summary

Official Symbol
murC
Official Full Name
UDP-N-acetylmuramate--L-alanine ligase
Primary source
ECOCYC:EG10619
Locus tag
b0091
See related
ASAP:ABE-0000324
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0092
Summary
PDB: [More information is available at EcoGene: EG10619].
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Genomic context

Sequence:
NC_000913.3 (100765..102240)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase Neighboring gene peptidoglycan glycosyltransferase FtsW Neighboring gene N-acetylglucosaminyl transferase Neighboring gene D-alanine--D-alanine ligase B Neighboring gene cell division protein FtsQ Neighboring gene cell division protein FtsA Neighboring gene cell division protein FtsZ

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IDA
Inferred from Direct Assay
more info
PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables UDP-N-acetylmuramate-L-alanine ligase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables UDP-N-acetylmuramate-L-alanine ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables acid-amino acid ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in cell division IEA
Inferred from Electronic Annotation
more info
 
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
 
involved_in peptidoglycan biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within peptidoglycan biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
UDP-N-acetylmuramate--L-alanine ligase
NP_414633.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    100765..102240
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414633.1 UDP-N-acetylmuramate--L-alanine ligase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414633.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8T5ZGV2, A0A8T6PMU6
    Conserved Domains (1) summary
    PRK00421
    Location:13484
    murC; UDP-N-acetylmuramate--L-alanine ligase; Provisional