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topB DNA topoisomerase III [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946141, updated on 19-Jan-2019

Summary

Gene symbol
topB
Gene description
DNA topoisomerase III
Primary source
EcoGene:EG11014
Locus tag
b1763
See related
ASAP:ABE-0005869; ECOCYC:EG11014
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1761; mutR
Summary
DNA topoisomerase III (Topo III) is a type I topoisomerase which can decatenate DNA; at high temperatures in vitro, the enzyme can also relax negative supercoils in DNA . [More information is available at EcoCyc: EG11014].

Genomic context

Sequence:
NC_000913.3 (1844999..1846960, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene glutamate dehydrogenase Neighboring gene DUF1266 domain-containing protein YnjI Neighboring gene selenide, water dikinase Neighboring gene putative oxidoreductase

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA topoisomerase type I activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
DNA recombination IMP
Inferred from Mutant Phenotype
more info
PubMed 
chromosome separation IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
DNA topoisomerase III
NP_416277.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1844999..1846960 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416277.1 DNA topoisomerase III [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416277.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P14294
    Conserved Domains (1) summary
    PRK07726
    Location:1642
    PRK07726; DNA topoisomerase III; Provisional
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