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sufC Fe-S cluster scaffold complex subunit SufC [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946128, updated on 10-Feb-2026
Official Symbol
sufC
Official Full Name
Fe-S cluster scaffold complex subunit SufC
Primary source
ECOCYC:G6908
Locus tag
b1682
See related
ASAP:ABE-0005619
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1678; ynhD
Summary
SufC is part of the protein machinery that is involved in the biosynthesis of iron-sulfur clusters. [More information is available at EcoCyc: G6908].
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Sequence:
NC_000913.3 (1761766..1762512, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene sulfur carrier protein SufE Neighboring gene L-cysteine desulfurase Neighboring gene Fe-S cluster scaffold complex subunit SufD Neighboring gene Fe-S cluster scaffold complex subunit SufB Neighboring gene iron-sulfur cluster insertion protein SufA

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. SufC hydrolyzes ATP and interacts with SufB from Thermotoga maritima. Rangachari K, et al. FEBS Lett, 2002 Mar 13. PMID 11943156
  2. Iron-sulfur (Fe-S) cluster assembly: the SufBCD complex is a new type of Fe-S scaffold with a flavin redox cofactor. Wollers S, et al. J Biol Chem, 2010 Jul 23. PMID 20460376, Free PMC Article
  3. Molecular dynamism of Fe-S cluster biosynthesis implicated by the structure of the SufC(2)-SufD(2) complex. Wada K, et al. J Mol Biol, 2009 Mar 20. PMID 19361433, Free PMC Article
  4. The SufBCD Fe-S scaffold complex interacts with SufA for Fe-S cluster transfer. Chahal HK, et al. Biochemistry, 2009 Nov 10. PMID 19810706, Free PMC Article
  5. The SufE protein and the SufBCD complex enhance SufS cysteine desulfurase activity as part of a sulfur transfer pathway for Fe-S cluster assembly in Escherichia coli. Outten FW, et al. J Biol Chem, 2003 Nov 14. PMID 12941942

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in iron-sulfur cluster assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within iron-sulfur cluster assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in iron-sulfur cluster assembly NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within response to radiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
part_of iron-sulfur cluster assembly complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of iron-sulfur cluster assembly complex IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
Fe-S cluster scaffold complex subunit SufC

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1761766..1762512 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416197.1 Fe-S cluster scaffold complex subunit SufC

    See identical proteins and their annotated locations for NP_416197.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A376S8K0
    Conserved Domains (1) summary
    PRK09580
    Location:1 → 248
    sufC; cysteine desulfurase ATPase component; Reviewed
Nucleotide Protein
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