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pqqL periplasmic metalloprotease [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946059, updated on 30-Jul-2025
Official Symbol
pqqL
Official Full Name
periplasmic metalloprotease
Primary source
ECOCYC:EG11744
Locus tag
b1494
See related
ASAP:ABE-0004979
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1488; pqqE; pqqM; yddC
Summary
First 26 aa are predicted to be a type I signal peptide. pqqL and yhiJ are paralogs. [More information is available at EcoGene: EG11744]. PqqL is a putative zinc peptidase by similarity . [More information is available at EcoCyc: EG11744].
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Sequence:
NC_000913.3 (1572407..1575202, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene L-glutamate:4-aminobutyrate antiporter Neighboring gene glutamate decarboxylase B Neighboring gene putative TonB-dependent receptor YddB Neighboring gene ABC transporter family protein YddA

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Complementation of Methylobacterium organophilum mutants affected in pyrroloquinoline quinone biosynthesis genes pqqE and pqqF by cloned Escherichia coli chromosomal DNA. Turlin E, et al. FEMS Microbiol Lett, 1991 Sep 15. PMID 1663886
  2. Mutants of Escherichia coli producing pyrroloquinoline quinone. Biville F, et al. J Gen Microbiol, 1991 Aug. PMID 1659611
  3. Protease-associated import systems are widespread in Gram-negative bacteria. Grinter R, et al. PLoS Genet, 2019 Oct. PMID 31613892, Free PMC Article
  4. Sequence and functional analysis of an Escherichia coli DNA fragment able to complement pqqE and pqqF mutants from Methylobacterium organophilum. Turlin E, et al. Biochimie, 1996. PMID 9116051
  5. DNA microarray-based identification of genes controlled by autoinducer 2-stimulated quorum sensing in Escherichia coli. DeLisa MP, et al. J Bacteriol, 2001 Sep. PMID 11514505, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables metallopeptidase activity ISM
Inferred from Sequence Model
more info
 PubMed 
enables peptidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
periplasmic metalloprotease

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1572407..1575202 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416011.1 periplasmic metalloprotease

    See identical proteins and their annotated locations for NP_416011.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1Q9KVC4, A0A1X3JI88, A0A236MIE1
    Conserved Domains (1) summary
    COG0612
    Location:23 → 454
    PqqL; Predicted Zn-dependent peptidase [General function prediction only]
Nucleotide Protein
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