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dmsD redox enzyme maturation protein DmsD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945987, updated on 6-May-2021

Summary

Gene symbol
dmsD
Gene description
redox enzyme maturation protein DmsD
Primary source
ASAP:ABE-0005314
Locus tag
b1591
See related
ECOCYC:G6849
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1586; ynfI
Summary
dmsD is the fifth gene in the dmsABC-like operon ynfEFGH-dmsD. torD, dmsD and ycdY are paralogs.Overexpressed YdcY and DmsD interfere with apoTorA maturation by TorD, independent of the TorA signal peptide (Ilbert, 2004). [More information is available at EcoGene: EG13847]. DmsD binds to the twin-arginine leaders of certain proteins, including dimethylsulfoxide (DMSO) reductase and trimethylamine N-oxide (TMAO) reductase that are translocated to the cytoplasmic membrane for the periplasm by the Sec-independent system that is termed Mtt (membrane targeting and transport) or more frequently Tat (twin-arginine translocation) . [More information is available at EcoCyc: G6849].
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Genomic context

Sequence:
NC_000913.3 (1664506..1665120)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative oxidoreductase YnfG Neighboring gene putative menaquinol dehydrogenase Neighboring gene putative chloride:H(+) antiporter ClcB Neighboring gene putative dethiobiotin synthetase Neighboring gene DNA-binding transcriptional repressor Mlc

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables signal sequence binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within chaperone-mediated protein folding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in extrinsic component of cytoplasmic side of plasma membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
redox enzyme maturation protein DmsD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1664506..1665120
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416108.2 redox enzyme maturation protein DmsD [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416108.2

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P69853
    Conserved Domains (1) summary
    PRK11621
    Location:1204
    PRK11621; Tat proofreading chaperone DmsD
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