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mhpR DNA-binding transcriptional activator MhpR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945938, updated on 26-Jun-2025
Official Symbol
mhpR
Official Full Name
DNA-binding transcriptional activator MhpR
Primary source
ECOCYC:G6201
Locus tag
b0346
See related
ASAP:ABE-0001191
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0343
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Sequence:
NC_000913.3 (367587..368420, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene beta-galactosidase Neighboring gene DNA-binding transcriptional repressor LacI Neighboring gene 3-(3-hydroxyphenyl)propanoate hydroxylase Neighboring gene 3-carboxyethylcatechol 2,3-dioxygenase

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. 3-Hydroxyphenylpropionate and phenylpropionate are synergistic activators of the MhpR transcriptional regulator from Escherichia coli. Manso I, et al. J Biol Chem, 2009 Aug 7. PMID 19520845, Free PMC Article
  2. Regulation of the mhp cluster responsible for 3-(3-hydroxyphenyl)propionic acid degradation in Escherichia coli. Torres B, et al. J Biol Chem, 2003 Jul 25. PMID 12748194
  3. Isolation and characterization of Escherichia coli mutants defective for phenylpropionate degradation. Burlingame RP, et al. J Bacteriol, 1986 Oct. PMID 3531186, Free PMC Article
  4. Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12. Ferrández A, et al. J Bacteriol, 1997 Apr. PMID 9098055, Free PMC Article
  5. Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12. Díaz E, et al. J Bacteriol, 1998 Jun. PMID 9603882, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. 3-Hydroxyphenylpropionate and phenylpropionate are synergistic activators of the MhpR transcriptional regulator from Escherichia coli
    Title: 3-Hydroxyphenylpropionate and phenylpropionate are synergistic activators of the MhpR transcriptional regulator from Escherichia coli.
  2. N-terminus verified by Edman degradation on complete protein
    Title: Regulation of the mhp cluster responsible for 3-(3-hydroxyphenyl)propionic acid degradation in Escherichia coli.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
DNA-binding transcriptional activator MhpR

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    367587..368420 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_414880.2 DNA-binding transcriptional activator MhpR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_414880.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0H3PFI0, A0ABC7ZMR9, B1LIN1
    Conserved Domains (1) summary
    PRK09834
    Location:7 → 268
    PRK09834; DNA-binding transcriptional regulator
Nucleotide Protein
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