Format

Send to:

Choose Destination

fnr DNA-binding transcriptional dual regulator FNR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945908, updated on 6-May-2021

Summary

Gene symbol
fnr
Gene description
DNA-binding transcriptional dual regulator FNR
Primary source
ASAP:ABE-0004475
Locus tag
b1334
See related
ECOCYC:EG10325
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1330; nirA; nirR; ossA; oxrA
Summary
FNR represses genes involved in aerobic respiration and activates genes required for anaerobic respiration. [More information is available at EcoGene: EG10325]. FNR is a dual DNA-binding transcriptional regulator which stimulates the transcription of many genes required for fermentation and anaerobic respiration. [More information is available at EcoCyc: EG10325].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (1398774..1399526, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF2534 domain-containing protein YnaJ Neighboring gene universal stress protein E Neighboring gene methylated-DNA--[protein]-cysteine S-methyltransferase Neighboring gene p-aminobenzoyl glutamate:H(+) symporter

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IDA
Inferred from Direct Assay
more info
PubMed 
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription activator activity IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA-binding transcription activator activity IPI
Inferred from Physical Interaction
more info
PubMed 
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
enables iron-sulfur cluster binding IDA
Inferred from Direct Assay
more info
PubMed 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables transcription cis-regulatory region binding IDA
Inferred from Direct Assay
more info
PubMed 
enables transcription cis-regulatory region binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
part_of protein-DNA complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of protein-DNA complex IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
DNA-binding transcriptional dual regulator FNR

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1398774..1399526 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415850.1 DNA-binding transcriptional dual regulator FNR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415850.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0A9E5
    Conserved Domains (1) summary
    PRK11161
    Location:11245
    PRK11161; fumarate/nitrate reduction transcriptional regulator Fnr
Support Center