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ycgZ putative two-component system connector protein YcgZ [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945885, updated on 30-Jul-2025
Official Symbol
ycgZ
Official Full Name
putative two-component system connector protein YcgZ
Primary source
ECOCYC:G6604
Locus tag
b1164
See related
ASAP:ABE-0003907
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1151
Summary
Blue light activation of the YgcE anti-repressor relieves YcgF repression of the cold-shock RpoS-activated small protein operon ycgZ-ymgA-ariR-ymgC operon; connector proteins AirR(YmgB) (at 28C) and YmgA (at 16C) stimulate colanic acid synthesis and inhibit curli production by an RcsA-independent activation of RcsB; RcsB activation is antagonized by connector protein YcgZ (Tschowr, 2009). ycgZ is induced three hours after cold shock in a pnp-dependent manner. [More information is available at EcoGene: EG14288].
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Sequence:
NC_000913.3 (1215789..1216025)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional repressor BluR Neighboring gene blue light- and temperature-regulated antirepressor BluF Neighboring gene putative two-component system connector protein YmgA Neighboring gene putative two-component system connector protein AriR

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The Escherichia coli MarA protein regulates the ycgZ-ymgABC operon to inhibit biofilm formation. Kettles RA, et al. Mol Microbiol, 2019 Nov. PMID 31518447, Free PMC Article
  2. Low temperature (23 degrees C) increases expression of biofilm-, cold-shock- and RpoS-dependent genes in Escherichia coli K-12. White-Ziegler CA, et al. Microbiology (Reading), 2008 Jan. PMID 18174134
  3. Molecular function and potential evolution of the biofilm-modulating blue light-signalling pathway of Escherichia coli. Tschowri N, et al. Mol Microbiol, 2012 Sep. PMID 22783906, Free PMC Article
  4. Identification of genes affecting lycopene accumulation in Escherichia coli using a shot-gun method. Kang MJ, et al. Biotechnol Bioeng, 2005 Sep 5. PMID 15898075
  5. The BLUF-EAL protein YcgF acts as a direct anti-repressor in a blue-light response of Escherichia coli. Tschowri N, et al. Genes Dev, 2009 Feb 15. PMID 19240136, Free PMC Article

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data identified the BluR binding site in the ycgZ promoter and observed that BluR also has residual affinity for the MlrA-dependent csgD promoter.
    Title: Molecular function and potential evolution of the biofilm-modulating blue light-signalling pathway of Escherichia coli.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to acidic pH EXP
Inferred from Experiment
more info
 PubMed 
involved_in cellular response to acidic pH IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of DNA-templated transcription IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Preferred Names
putative two-component system connector protein YcgZ

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1215789..1216025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415682.1 putative two-component system connector protein YcgZ

    See identical proteins and their annotated locations for NP_415682.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8S0FX35
    Conserved Domains (1) summary
    pfam10798
    Location:26 → 58
    YmgB; Biofilm development protein YmgB/AriR
Nucleotide Protein
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