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btuC vitamin B12 ABC transporter membrane subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945877, updated on 23-Nov-2023

Summary

Gene symbol
btuC
Gene description
vitamin B12 ABC transporter membrane subunit
Primary source
ASAP:ABE-0005712
Locus tag
b1711
See related
ECOCYC:EG10127
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1709
Summary
BtuC is the integral membrane component of BtuCD, an ABC type vitamin B12 uptake system. [More information is available at EcoCyc: EG10127].
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Genomic context

Sequence:
NC_000913.3 (1794172..1795152, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene vitamin B12 ABC transporter ATP binding subunit Neighboring gene thioredoxin/glutathione peroxidase BtuE Neighboring gene integration host factor subunit alpha Neighboring gene phenylalanine--tRNA ligase subunit beta

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ABC-type vitamin B12 transporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables vitamin transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cobalamin transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within cobalamin transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cobalamin transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in cobalamin transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within cobalamin transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in vitamin transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of BtuCD complex IPI
Inferred from Physical Interaction
more info
PubMed 
part_of cobalamin transport complex IPI
Inferred from Physical Interaction
more info
PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
vitamin B12 ABC transporter membrane subunit
NP_416226.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1794172..1795152 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416226.1 vitamin B12 ABC transporter membrane subunit [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416226.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376S8K3, A0A5B9AM81
    Conserved Domains (1) summary
    PRK03784
    Location:1326
    PRK03784; vtamin B12-transporter permease; Provisional