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sapA putative periplasmic binding protein SapA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945873, updated on 4-Apr-2024

Summary

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Gene symbol
sapA
Gene description
putative periplasmic binding protein SapA
Primary source
ASAP:ABE-0004354
Locus tag
b1294
See related
ECOCYC:G2002
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1289
Summary
Characterized initially in Salmonella. [More information is available at EcoGene: EG20254]. SapABCDF (Sensitive to antimicrobial peptides) is a member of the ATP Binding Cassette (ABC) transporter superfamily . [More information is available at EcoCyc: G2002].
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Genomic context

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Sequence:
NC_000913.3 (1355467..1357110, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putrescine ABC exporter ATP binding protein SapF Neighboring gene putrescine ABC exporter ATP binding protein SapD Neighboring gene putrescine ABC exporter membrane protein SapC Neighboring gene putrescine ABC exporter membrane subunit SapB Neighboring gene DUF2543 domain-containing protein YmjA Neighboring gene putrescine:H(+) symporter PuuP Neighboring gene protein YmjE

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A Salmonella protein that is required for resistance to antimicrobial peptides and transport of potassium. Parra-Lopez C, et al. EMBO J, 1994 Sep 1. PMID 8076592, Free PMC Article
  2. Resistance to host antimicrobial peptides is necessary for Salmonella virulence. Groisman EA, et al. Proc Natl Acad Sci U S A, 1992 Dec 15. PMID 1465423, Free PMC Article
  3. Identification of the ABC protein SapD as the subunit that confers ATP dependence to the K+-uptake systems Trk(H) and Trk(G) from Escherichia coli K-12. Harms C, et al. Microbiology (Reading), 2001 Nov. PMID 11700350
  4. Requirement of a large K+-uptake capacity and of extracytoplasmic protease activity for protamine resistance of Escherichia coli. Stumpe S, et al. Arch Microbiol, 1997 Feb-Mar. PMID 9133319
  5. ATP-binding cassette transporters in Escherichia coli. Moussatova A, et al. Biochim Biophys Acta, 2008 Sep. PMID 18634750

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables peptide transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in peptide transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in peptide transport NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IEA
Inferred from Electronic Annotation
more info
  
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in outer membrane-bounded periplasmic space IEA
Inferred from Electronic Annotation
more info
  
located_in outer membrane-bounded periplasmic space RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative periplasmic binding protein SapA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1355467..1357110 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415810.1 putative periplasmic binding protein SapA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415810.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A3L9IEP1
    Conserved Domains (1) summary
    PRK15109
    Location:1 → 547
    PRK15109; antimicrobial peptide ABC transporter periplasmic binding protein SapA; Provisional
Nucleotide Protein
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