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osmB osmotically-inducible lipoprotein OsmB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945866, updated on 19-Nov-2025
Official Symbol
osmB
Official Full Name
osmotically-inducible lipoprotein OsmB
Primary source
ECOCYC:EG10679
Locus tag
b1283
See related
ASAP:ABE-0004309
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1278
Summary
First 23 aa are a type II signal peptide. [More information is available at EcoGene: EG10679]. The osmB gene of Escherichia coli has been shown to be inducible by both osmotic stress and growth phase signals . [More information is available at EcoCyc: EG10679].
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Sequence:
NC_000913.3 (1343110..1343328, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene lipopolysaccharide assembly protein B Neighboring gene orotidine-5'-phosphate decarboxylase Neighboring gene putative translation factor Neighboring gene DNA-binding transcriptional dual regulator YciT Neighboring gene UPF0509 family protein YciZ

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Amyloid fibril formation requires a chemically discriminating nucleation event: studies of an amyloidogenic sequence from the bacterial protein OsmB. Jarrett JT, et al. Biochemistry, 1992 Dec 15. PMID 1463722
  2. Transcription of osmB, a gene encoding an Escherichia coli lipoprotein, is regulated by dual signals. Osmotic stress and stationary phase. Jung JU, et al. J Biol Chem, 1990 Jun 25. PMID 1693921
  3. Sequence of an osmotically inducible lipoprotein gene. Jung JU, et al. J Bacteriol, 1989 Jan. PMID 2644204, Free PMC Article
  4. Transcriptional regulation of the cytR repressor gene of Escherichia coli: autoregulation and positive control by the cAMP/CAP complex. Gerlach P, et al. Mol Microbiol, 1990 Mar. PMID 2162467
  5. Multistress regulation in Escherichia coli: expression of osmB involves two independent promoters responding either to sigmaS or to the RcsCDB His-Asp phosphorelay. Boulanger A, et al. J Bacteriol, 2005 May. PMID 15838058, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. osmB appears as another example of a multistress-responsive gene whose transcription involves both a sigma(S)-dependent promoter and a second one independent of sigma(S) but controlled by stress-specific transcription factors.
    Title: Multistress regulation in Escherichia coli: expression of osmB involves two independent promoters responding either to sigmaS or to the RcsCDB His-Asp phosphorelay.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
acts_upstream_of_or_within response to osmotic stress IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
osmotically-inducible lipoprotein OsmB

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1343110..1343328 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415799.1 osmotically-inducible lipoprotein OsmB

    See identical proteins and their annotated locations for NP_415799.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5B9AN39
    Conserved Domains (1) summary
    PRK10540
    Location:1 → 72
    PRK10540; osmotically-inducible lipoprotein OsmB
Nucleotide Protein
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