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tktB transketolase 2 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945865, updated on 6-May-2021

Summary

Gene symbol
tktB
Gene description
transketolase 2
Primary source
ASAP:ABE-0008117
Locus tag
b2465
See related
ECOCYC:EG12100
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2460
Summary
Consistently co-purifies with the degradosome. [More information is available at EcoGene: EG12100]. TktB is responsible for the minor transketolase activity in Escherichia coli, and TktA is responsible for the major transketolase activity . [More information is available at EcoCyc: EG12100].
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Genomic context

Sequence:
NC_000913.3 (2579636..2581639)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene NADP(+)-dependent malate dehydrogenase Neighboring gene transaldolase A Neighboring gene DUF1176 domain-containing protein YpfG Neighboring gene GDP-mannose hydrolase

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transketolase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transketolase activity IEA
Inferred from Electronic Annotation
more info
 
enables transketolase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
involved_in pentose-phosphate shunt IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
acts_upstream_of_or_within pentose-phosphate shunt, non-oxidative branch IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
transketolase 2
NP_416960.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2579636..2581639
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416960.1 transketolase 2 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416960.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P33570
    Conserved Domains (1) summary
    PRK12753
    Location:1662
    PRK12753; transketolase; Reviewed
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