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sohB S49 peptidase family protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945858, updated on 26-Mar-2025
Official Symbol
sohB
Official Full Name
S49 peptidase family protein
Primary source
ECOCYC:EG10956
Locus tag
b1272
See related
ASAP:ABE-0004267
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1266
Summary
SohB is homologous to inner membrane protease IV, which digests cleaved signal peptides. [More information is available at EcoGene: EG10956]. SohB might be a periplasmic protease, based on sequence analysis and the genetic interaction between sohB and htrA . [More information is available at EcoCyc: EG10956].
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Sequence:
NC_000913.3 (1329332..1330381)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 23S rRNA pseudouridine(2605) synthase Neighboring gene cobinamide/cobalamin adenosyltransferase Neighboring gene putative oxidoreductase Neighboring gene protein YciN Neighboring gene DNA topoisomerase 1

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Identification of the Escherichia coli sohB gene, a multicopy suppressor of the HtrA (DegP) null phenotype. Baird L, et al. J Bacteriol, 1991 Sep. PMID 1885549, Free PMC Article
  2. Complete nucleotide sequence of the topA gene encoding Escherichia coli DNA topoisomerase I. Tse-Dinh YC, et al. J Mol Biol, 1986 Oct 5. PMID 3029379
  3. RpoS-dependent regulation of genes expressed at late stationary phase in Escherichia coli. Talukder AA, et al. FEBS Lett, 1996 May 20. PMID 8647276
  4. Membranome: a database for proteome-wide analysis of single-pass membrane proteins. Lomize AL, et al. Nucleic Acids Res, 2017 Jan 4. PMID 27510400, Free PMC Article
  5. Comparison of SDS- and methanol-assisted protein solubilization and digestion methods for Escherichia coli membrane proteome analysis by 2-D LC-MS/MS. Zhang N, et al. Proteomics, 2007 Feb. PMID 17309111

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within proteolysis IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
Preferred Names
S49 peptidase family protein

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1329332..1330381
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415788.1 S49 peptidase family protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415788.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376MWD7
    Conserved Domains (1) summary
    PRK11778
    Location:3 → 341
    PRK11778; putative inner membrane peptidase; Provisional
Nucleotide Protein
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