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tonB Ton complex subunit TonB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945843, updated on 6-May-2021

Summary

Gene symbol
tonB
Gene description
Ton complex subunit TonB
Primary source
ASAP:ABE-0004196
Locus tag
b1252
See related
ECOCYC:EG11012
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1246; exbA; T1rec
Summary
Periplasmic TonB is attached to the cytoplasmic membrane by a signal anchor and interacts with outer membrane proteins, thus TonB spans the periplasmic space. [More information is available at EcoGene: EG11012]. TonB is a cytoplasmic membrane protein which transduces the proton motive force (pmf) of the cytoplasmic membrane to the outer membrane active transporters thus providing the energy source required for the import of iron-siderophore complexes and vitamin B12 across the outer membrane . [More information is available at EcoCyc: EG11012].
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Genomic context

Sequence:
NC_000913.3 (1311089..1311808)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene K(+) channel Kch Neighboring gene protein YciI Neighboring gene acyl-CoA thioesterase YciA Neighboring gene inner membrane protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables energy transducer activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables energy transducer activity IDA
Inferred from Direct Assay
more info
PubMed 
enables energy transducer activity IEA
Inferred from Electronic Annotation
more info
 
enables energy transducer activity TAS
Traceable Author Statement
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables protein domain specific binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables siderophore transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in integral component of external side of plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
PubMed 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
PubMed 
located_in outer membrane-bounded periplasmic space IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
part_of plasma membrane protein complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of plasma membrane protein complex IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1311089..1311808
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415768.1 Ton complex subunit TonB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415768.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P02929
    Conserved Domains (1) summary
    PRK10819
    Location:1239
    PRK10819; transport protein TonB; Provisional
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