U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

kch K(+) channel Kch [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945841, updated on 23-Apr-2026
Official Symbol
kch
Official Full Name
K(+) channel Kch
Primary source
ECOCYC:EG11606
Locus tag
b1250
See related
ASAP:ABE-0004189
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1244
Summary
Consistently co-purifies with the degradosome. [More information is available at EcoGene: EG11606]. Kch is a member of the Voltage-gated Ion Channel (VIC) Superfamily of transporters . [More information is available at EcoCyc: EG11606].
Try the new Gene page
Try the new Transcripts and proteins table
Sequence:
NC_000913.3 (1309016..1310269, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene cardiolipin synthase A Neighboring gene uncharacterized protein YciY Neighboring gene protein YciI Neighboring gene Ton complex subunit TonB

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Functional properties of Kch, a prokaryotic homologue of eukaryotic potassium channels. Munsey TS, et al. Biochem Biophys Res Commun, 2002 Sep 13. PMID 12220501
  2. Evolutionary origins of ion channels. Ranganathan R. Proc Natl Acad Sci U S A, 1994 Apr 26. PMID 7513423, Free PMC Article
  3. Voltage gating of ion channels. Sigworth FJ. Q Rev Biophys, 1994 Feb. PMID 7520590
  4. Membrane topology of Kch, a putative K+ channel from Escherichia coli. Johansson M, et al. J Biol Chem, 1996 Oct 18. PMID 8824224
  5. Recombinant expression, purification and characterization of Kch, a putative Escherichia coli potassium channel protein. Voges D, et al. FEBS Lett, 1998 Jun 5. PMID 9657392

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The structure of Kch, a channel of this type from Escherichia coli, in a lipid environment using electron crystallography.
    Title: Free RCK arrangement in Kch, a putative escherichia coli potassium channel, as suggested by electron crystallography.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables potassium channel activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables potassium channel activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
involved_in potassium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in potassium ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within potassium ion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
 PubMed 
Preferred Names
K(+) channel Kch

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1309016..1310269 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415766.1 K(+) channel Kch

    See identical proteins and their annotated locations for NP_415766.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8S7R7N5
    Conserved Domains (1) summary
    PRK10537
    Location:3 → 402
    PRK10537; voltage-gated potassium channel protein
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.