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kch [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945841, updated on 11-Sep-2024

Summary

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Official Symbol
kch
Primary source
ECOCYC:EG11606
Locus tag
b1250
See related
ASAP:ABE-0004189
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1244
Summary
Consistently co-purifies with the degradosome. [More information is available at EcoGene: EG11606]. Kch is a member of the Voltage-gated Ion Channel (VIC) Superfamily of transporters . [More information is available at EcoCyc: EG11606].
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Genomic context

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Sequence:
NC_000913.3 (1309016..1310269, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene cardiolipin synthase A Neighboring gene uncharacterized protein YciY Neighboring gene protein YciI Neighboring gene Ton complex subunit TonB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Free RCK arrangement in Kch, a putative escherichia coli potassium channel, as suggested by electron crystallography. Kuang Q, et al. Structure, 2015 Jan 6. PMID 25497729
  2. Assembly of Kch, a putative potassium channel from Escherichia coli. Lundbäck AK, et al. J Struct Biol, 2009 Nov. PMID 19631752
  3. Gain-of-function mutations indicate that Escherichia coli Kch forms a functional K+ conduit in vivo. Kuo MM, et al. EMBO J, 2003 Aug 15. PMID 12912904, Free PMC Article
  4. Functional properties of Kch, a prokaryotic homologue of eukaryotic potassium channels. Munsey TS, et al. Biochem Biophys Res Commun, 2002 Sep 13. PMID 12220501
  5. Analysis of a putative voltage-gated prokaryotic potassium channel. Ungar D, et al. Eur J Biochem, 2001 Oct. PMID 11606201

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The structure of Kch, a channel of this type from Escherichia coli, in a lipid environment using electron crystallography.
    Title: Free RCK arrangement in Kch, a putative escherichia coli potassium channel, as suggested by electron crystallography.
Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables potassium channel activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables potassium channel activity ISA
Inferred from Sequence Alignment
more info
 PubMed 
Process Evidence Code Pubs
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in potassium ion transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in potassium ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within potassium ion transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
part_of protein-containing complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
K(+) channel Kch

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1309016..1310269 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415766.1 K(+) channel Kch [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415766.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7R7N5
    Conserved Domains (1) summary
    PRK10537
    Location:3 → 402
    PRK10537; voltage-gated potassium channel protein
Nucleotide Protein
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