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adhE fused acetaldehyde-CoA dehydrogenase and iron-dependent alcohol dehydrogenasealdehyde/alcohol dehydrogenase AdhE [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945837, updated on 3-Dec-2024

Summary

Official Symbol
adhE
Official Full Name
fused acetaldehyde-CoA dehydrogenase and iron-dependent alcohol dehydrogenasealdehyde/alcohol dehydrogenase AdhE
Primary source
ECOCYC:EG10031
Locus tag
b1241
See related
ASAP:ABE-0004164
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
adhC; ana; ECK1235
Summary
The reported PFL deactivase activity of AdhE (Kessler, 1991, 1992) could not be reproduced (Nnyepi, 2007). [More information is available at EcoGene: EG10031]. A homopolymeric protein with three Fe++-dependent catalytic functions: alcohol dehydrogenase, acetaldehyde dehydrogenase and pyruvate formate-lyase deactivase. [More information is available at EcoCyc: EG10031].
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Genomic context

Sequence:
NC_000913.3 (1295446..1298121, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene thymidine/deoxyuridine kinase Neighboring gene pseudo Neighboring gene protein YchT Neighboring gene MarC family putative inner membrane protein YchE

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

General protein information

Preferred Names
fused acetaldehyde-CoA dehydrogenase and iron-dependent alcohol dehydrogenasealdehyde/alcohol dehydrogenase AdhE
NP_415757.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1295446..1298121 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415757.1 fused acetaldehyde-CoA dehydrogenase and iron-dependent alcohol dehydrogenasealdehyde/alcohol dehydrogenase AdhE [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415757.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAN3GG84
    Conserved Domains (1) summary
    PRK13805
    Location:1862
    PRK13805; bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional