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clsA cardiolipin synthase A [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945821, updated on 6-Jun-2024

Summary

Gene symbol
clsA
Gene description
cardiolipin synthase A
Primary source
ASAP:ABE-0004186
Locus tag
b1249
See related
ECOCYC:EG11608
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
cls; ECK1243; nov; yciJ
Summary
Overexpression causes filamentous biofilm formation. [More information is available at EcoGene: EG11608].
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Genomic context

Sequence:
NC_000913.3 (1307185..1308645, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene murein tripeptide ABC transporter/oligopeptide ABC transporter ATP binding subunit OppD Neighboring gene murein tripeptide ABC transporter/oligopeptide ABC transporter ATP binding subunit OppF Neighboring gene DUF440 domain-containing protein YciU Neighboring gene uncharacterized protein YciY Neighboring gene K(+) channel Kch

Bibliography

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables cardiolipin synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables cardiolipin synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables cardiolipin synthase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphatidyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables phosphotransferase activity, for other substituted phosphate groups IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cardiolipin biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cardiolipin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in cardiolipin biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in phospholipid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell pole IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cardiolipin synthase A
NP_415765.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1307185..1308645 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415765.1 cardiolipin synthase A [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415765.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9AN58, A0A8T5ZB79
    Conserved Domains (1) summary
    PRK01642
    Location:5486
    cls; cardiolipin synthetase; Reviewed