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oppC murein tripeptide ABC transporter/oligopeptide ABC transporter inner membrane subunit OppC [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945810, updated on 19-Feb-2025

Summary

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Official Symbol
oppC
Official Full Name
murein tripeptide ABC transporter/oligopeptide ABC transporter inner membrane subunit OppC
Primary source
ECOCYC:EG10676
Locus tag
b1245
See related
ASAP:ABE-0004176
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1239
Summary
OppC is an integral membrane component of the oligopeptide ABC transporter and the murein tripeptide ABC transporter. [More information is available at EcoCyc: EG10676].
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Genomic context

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Sequence:
NC_000913.3 (1303834..1304742)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene oligopeptide ABC transporter periplasmic binding protein Neighboring gene murein tripeptide ABC transporter/oligopeptide ABC transporter inner membrane subunit OppB Neighboring gene murein tripeptide ABC transporter/oligopeptide ABC transporter ATP binding subunit OppD Neighboring gene murein tripeptide ABC transporter/oligopeptide ABC transporter ATP binding subunit OppF Neighboring gene DUF440 domain-containing protein YciU

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic organization of the oligopeptide permease (opp) locus of Salmonella typhimurium and Escherichia coli. Hogarth BG, et al. J Bacteriol, 1983 Mar. PMID 6338001, Free PMC Article
  2. The structural basis of sequence-independent peptide binding by OppA protein. Tame JR, et al. Science, 1994 Jun 10. PMID 8202710
  3. Genetic analysis of Escherichia coli oligopeptide transport mutants. Andrews JC, et al. J Bacteriol, 1985 Feb. PMID 2981814, Free PMC Article
  4. The periplasmic murein peptide-binding protein MppA is a negative regulator of multiple antibiotic resistance in Escherichia coli. Li H, et al. J Bacteriol, 1999 Aug. PMID 10438753, Free PMC Article
  5. Structure determination of OppA at 2.3 A resolution using multiple-wavelength anomalous dispersion methods. Glover ID, et al. Acta Crystallogr D Biol Crystallogr, 1995 Jan 1. PMID 15299334

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. In vivo OppC functionality was determined by constructing an OppC gene deletion strain. OppC was shown to be essential for peptide uptake, and non-essential for cell viability
    Title: Detection of soluble expression and in vivo interactions of the inner membrane protein OppC using green fluorescent protein.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables peptidoglycan peptide transmembrane transporter activity EXP
Inferred from Experiment
more info
 PubMed 
enables peptidoglycan peptide transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in oligopeptide import across plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in peptide transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within peptidoglycan-associated peptide transport EXP
Inferred from Experiment
more info
 PubMed 
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in tripeptide import across plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
murein tripeptide ABC transporter/oligopeptide ABC transporter inner membrane subunit OppC
NP_415761.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1303834..1304742
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415761.1 murein tripeptide ABC transporter/oligopeptide ABC transporter inner membrane subunit OppC [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415761.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0H3PMS2, A0A221BH49, A0A376K2C3, A0A5B9AKE3, A0AAN4NX40
    Conserved Domains (1) summary
    PRK15406
    Location:1 → 302
    PRK15406; oligopeptide ABC transporter permease OppC; Provisional
Nucleotide Protein
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