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chaC [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945793, updated on 11-Sep-2024

Summary

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Official Symbol
chaC
Primary source
ECOCYC:EG12403
Locus tag
b1218
See related
ASAP:ABE-0004089
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1212
Summary
A chaC mutant shows a defect in swarming motility, but no significant defect in swimming motility . [More information is available at EcoCyc: EG12403].
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Genomic context

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Sequence:
NC_000913.3 (1272507..1273202)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene Na(+)/K(+):H(+) antiporter ChaA Neighboring gene putative cation transport regulator ChaB Neighboring gene DsrE/F sulfur relay family protein YchN Neighboring gene putative invasin YchO

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and characterization of a putative Ca2+/H+ antiporter gene from Escherichia coli upon functional complementation of Na+/H+ antiporter-deficient strains by the overexpressed gene. Ivey DM, et al. J Biol Chem, 1993 May 25. PMID 8496184
  2. Metabolic context and possible physiological themes of sigma(54)-dependent genes in Escherichia coli. Reitzer L, et al. Microbiol Mol Biol Rev, 2001 Sep. PMID 11528004, Free PMC Article
  3. ChaC2, an Enzyme for Slow Turnover of Cytosolic Glutathione. Kaur A, et al. J Biol Chem, 2017 Jan 13. PMID 27913623, Free PMC Article
  4. A comprehensive library of fluorescent transcriptional reporters for Escherichia coli. Zaslaver A, et al. Nat Methods, 2006 Aug. PMID 16862137
  5. A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map. Oshima T, et al. DNA Res, 1996 Jun 30. PMID 8905232

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables gamma-glutamylcyclotransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glutathione specific gamma-glutamylcyclotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glutathione specific gamma-glutamylcyclotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within glutathione catabolic process EXP
Inferred from Experiment
more info
 PubMed 
involved_in glutathione catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glutathione catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
glutathione-specific gamma-glutamylcyclotransferase
NP_415736.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1272507..1273202
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415736.2 glutathione-specific gamma-glutamylcyclotransferase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415736.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A826P7V8
    Conserved Domains (1) summary
    COG3703
    Location:34 → 224
    ChaC; Cation transport regulator ChaC [Inorganic ion transport and metabolism]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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