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dhaM dihydroxyacetone kinase subunit M [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945749, updated on 6-Jul-2026
Official Symbol
dhaM
Official Full Name
dihydroxyacetone kinase subunit M
Primary source
ECOCYC:EG12399
Locus tag
b1198
See related
ASAP:ABE-0004024
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
dhaH; ECK1186; ptsD; ycgC
Summary
DhaM is phosphorylated by PTS proteins HPr and Protein I. [More information is available at EcoGene: EG12399]. The M subunit is homologous to certain components of PTS: to a domain of EI, to HPr, and to the AB domains of EII. [More information is available at EcoCyc: EG12399].
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Sequence:
NC_000913.3 (1247696..1249114, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein YcgY Neighboring gene periplasmic trehalase Neighboring gene dihydroxyacetone kinase subunit L Neighboring gene dihydroxyacetone kinase subunit K

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Analysis and DNA sequence of the osmoregulated treA gene encoding the periplasmic trehalase of Escherichia coli K12. Gutierrez C, et al. Mol Gen Genet, 1989 Jun. PMID 2671658
  2. A mechanism of covalent substrate binding in the x-ray structure of subunit K of the Escherichia coli dihydroxyacetone kinase. Siebold C, et al. Proc Natl Acad Sci U S A, 2003 Jul 8. PMID 12813127, Free PMC Article
  3. From ATP as substrate to ADP as coenzyme: functional evolution of the nucleotide binding subunit of dihydroxyacetone kinases. Bächler C, et al. J Biol Chem, 2005 May 6. PMID 15753087
  4. An inducible phosphoenolpyruvate: dihydroxyacetone phosphotransferase system in Escherichia coli. Jin RZ, et al. J Gen Microbiol, 1984 Jan. PMID 6368745
  5. Functional genomic studies of dihydroxyacetone utilization in Escherichia coli. Paulsen IT, et al. Microbiology (Reading), 2000 Oct. PMID 11021910

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables phosphoenolpyruvate-glycerone phosphotransferase activity EXP
Inferred from Experiment
more info
 PubMed 
enables phosphoenolpyruvate-glycerone phosphotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphoenolpyruvate-glycerone phosphotransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transferase activity, transferring phosphorus-containing groups IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in carbohydrate phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in carbohydrate phosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in glycerol catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of transferase complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of transferase complex IPI
Inferred from Physical Interaction
more info
 PubMed 
Preferred Names
dihydroxyacetone kinase subunit M
NP_415716.4

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1247696..1249114 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415716.4 dihydroxyacetone kinase subunit M

    See identical proteins and their annotated locations for NP_415716.4

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0H2YYB0
    Conserved Domains (1) summary
    PRK11377
    Location:1 → 472
    PRK11377; dihydroxyacetone kinase subunit M; Provisional
Nucleotide Protein
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