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lsrA Autoinducer-2 ABC transporter ATP binding subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945680, updated on 19-Nov-2025
Official Symbol
lsrA
Official Full Name
Autoinducer-2 ABC transporter ATP binding subunit
Primary source
ECOCYC:G6800
Locus tag
b1513
See related
ASAP:ABE-0005056
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1506; ego; ydeX
Summary
LsrA is paralogous to ribose transport ATPase RbsA. [More information is available at EcoGene: EG13806]. LsrA is an ATP-binding component of a predicted ATP-dependent sugar transporter. [More information is available at EcoCyc: G6800].
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Sequence:
NC_000913.3 (1601490..1603025)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene autoinducer-2 kinase Neighboring gene DNA-binding transcriptional repressor LsrR Neighboring gene Autoinducer-2 ABC transporter membrane subunit LsrC Neighboring gene Autoinducer-2 ABC transporter membrane subunit LsrD Neighboring gene Autoinducer-2 ABC transporter periplasmic binding protein

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. LsrR-binding site recognition and regulatory characteristics in Escherichia coli AI-2 quorum sensing. Xue T, et al. Cell Res, 2009 Nov. PMID 19636340
  2. Interference with AI-2-mediated bacterial cell-cell communication. Xavier KB, et al. Nature, 2005 Sep 29. PMID 16193054, Free PMC Article
  3. The LuxS-dependent autoinducer AI-2 controls the expression of an ABC transporter that functions in AI-2 uptake in Salmonella typhimurium. Taga ME, et al. Mol Microbiol, 2001 Nov. PMID 11722742
  4. Global gene expression in Escherichia coli biofilms. Schembri MA, et al. Mol Microbiol, 2003 Apr. PMID 12657059
  5. Regulation of uptake and processing of the quorum-sensing autoinducer AI-2 in Escherichia coli. Xavier KB, et al. J Bacteriol, 2005 Jan. PMID 15601708, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in autoinducer AI-2 transmembrane transport NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in quorum sensing NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
Autoinducer-2 ABC transporter ATP binding subunit
NP_416030.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1601490..1603025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416030.1 Autoinducer-2 ABC transporter ATP binding subunit

    See identical proteins and their annotated locations for NP_416030.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A376K072
    Conserved Domains (1) summary
    PRK15439
    Location:1 → 511
    PRK15439; autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Nucleotide Protein
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