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rplY 50S ribosomal subunit protein L25 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945618, updated on 17-Dec-2024
Official Symbol
rplY
Official Full Name
50S ribosomal subunit protein L25
Primary source
ECOCYC:EG10885
Locus tag
b2185
See related
ASAP:ABE-0007231
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2179
Summary
rplY is a non-essential gene as judged by the ability to recombineer haploid deletions (Baba, 2006; Korepanov, 2006). [More information is available at EcoGene: EG10885]. The L25 protein is a component of the 50S subunit of the ribosome and binds to 5S rRNA. [More information is available at EcoCyc: EG10885].
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Sequence:
NC_000913.3 (2282517..2282801)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 16S rRNA pseudouridine(516) synthase Neighboring gene putative DNA repair helicase RadD Neighboring gene nucleoid-associated protein YejK Neighboring gene DUF1414 domain-containing protein YejL

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. The primary structure of the 5 S RNA binding protein L25 from Escherichia coli ribosomes. Dovgas NV, et al. FEBS Lett, 1975 May 15. PMID 1093874
  2. Long-residency hydration, cation binding, and dynamics of loop E/helix IV rRNA-L25 protein complex. Réblová K, et al. Biophys J, 2004 Nov. PMID 15339800, Free PMC Article
  3. Assignment of resonances of exchangeable protons in the NMR spectrum of the complex formed by Escherichia coli ribosomal protein L25 and uniformly nitrogen-15 enriched 5 S RNA fragment. Kime MJ. FEBS Lett, 1984 Oct 1. PMID 6383867
  4. Crystallization of a ribonuclease-resistant fragment of Escherichia coli 5 S ribosomal RNA and its complex with protein L25. Abdel-Meguid SS, et al. J Mol Biol, 1983 Dec 5. PMID 6197527
  5. [Structural behavior of RNA-binding proteins in free and complex states: ribosomal protein L25 and 5S RNA from Escherichia coli]. Chigradze IuN. Mol Biol (Mosk), 2008 Jul-Aug. PMID 18856069

See all (41) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The contact with protein L25 is important for the retention of protein L16 within the Escherichia coli ribosome in vivo.
    Title: Role of Protein L25 and Its Contact with Protein L16 in Maintaining the Active State of Escherichia coli Ribosomes in vivo.
  2. The rplY expression regulation represents one more example of regulatory pathways that control ribosome biogenesis in Escherichia coli and related bacteria.
    Title: Regulation of the rplY gene encoding 5S rRNA binding protein L25 in Escherichia coli and related bacteria.
  3. N-terminus verified by Edman degradation on complete protein
    Title: Small genes/gene-products in Escherichia coli K-12.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 5S rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 5S rRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables 5S rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within negative regulation of translation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to radiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in ribosomal large subunit assembly IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within translation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
50S ribosomal subunit protein L25

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2282517..2282801
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416690.1 50S ribosomal subunit protein L25 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416690.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AAD2S062
    Conserved Domains (1) summary
    PRK05943
    Location:1 → 94
    PRK05943; 50S ribosomal protein L25; Reviewed
Nucleotide Protein
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