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ndk nucleoside diphosphate kinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945611, updated on 29-Sep-2023

Summary

Gene symbol
ndk
Gene description
nucleoside diphosphate kinase
Primary source
ASAP:ABE-0008291
Locus tag
b2518
See related
ECOCYC:EG10650
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2514
Summary
Binds TrxA (Kumar, 2004). [More information is available at EcoGene: EG10650]. Nucleoside diphosphate kinase catalyzes the reaction in which the terminal phosphate of a nucleoside-triphosphate is transferred to a nucleoside-diphosphate. [More information is available at EcoCyc: EG10650].
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Genomic context

Sequence:
NC_000913.3 (2644433..2644864, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene cytoskeleton protein RodZ Neighboring gene 23S rRNA m(2)A2503 methyltransferase/tRNA m(2)A37 methyltransferase Neighboring gene peptidoglycan glycosyltransferase PbpC Neighboring gene alpha2-macroglobulin

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleoside diphosphate kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables nucleoside diphosphate kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables nucleoside diphosphate kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in CTP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in GTP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in UTP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in nucleotide metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
 
involved_in purine nucleotide metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in pyrimidine nucleotide metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
nucleoside diphosphate kinase
NP_417013.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2644433..2644864 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417013.1 nucleoside diphosphate kinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417013.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P0A763
    UniProtKB/TrEMBL
    A0A826U4H6, A0A8S7YE76, A0A9P2GFR1, W1ETF0
    Conserved Domains (1) summary
    PRK00668
    Location:3135
    ndk; mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated