Format

Send to:

Choose Destination

pgaA partially deacetylated poly-beta-1,6-N-acetyl-D-glucosamine outer membrane porin [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945596, updated on 18-Nov-2018

Summary

Gene symbol
pgaA
Gene description
partially deacetylated poly-beta-1,6-N-acetyl-D-glucosamine outer membrane porin
Primary source
EcoGene:EG13865
Locus tag
b1024
See related
ASAP:ABE-0003469; ECOCYC:G6531
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1014; hmsH; ycdS
Summary
PgaA is homolgous to Y. pestis hemin storage protein HmsH, but is unable to complement hmsH mutations. [More information is available at EcoGene: EG13865]. The pgaABCD locus is required for the synthesis of a cell-bound hexosamine-rich polysaccharide, which was identified as a linear polymer of beta-1,6-N-acetylglucosamine residues (PGA), an adhesin essential in biofilm formation . [More information is available at EcoCyc: G6531].

Genomic context

Sequence:
NC_000913.3 (1089866..1092289, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene poly-N-acetyl-D-glucosamine synthase subunit PgaD Neighboring gene poly-N-acetyl-D-glucosamine synthase subunit PgaC Neighboring gene poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase and beta-1,6 glycoside hydrolase Neighboring gene putative diguanylate cyclase DgcT Neighboring gene IS3 element protein InsF Neighboring gene IS3 element protein InsE

Pathways from BioSystems

  • Biofilm formation - Escherichia coli, organism-specific biosystem (from KEGG)
    Biofilm formation - Escherichia coli, organism-specific biosystemBacteria inhabiting a biofilm are protected from physical stress, antimicrobials, and the host immune system, and thereby cause severe medical, environmental, and technical problems. Biofilm formatio...
  • Biofilm formation - Escherichia coli, conserved biosystem (from KEGG)
    Biofilm formation - Escherichia coli, conserved biosystemBacteria inhabiting a biofilm are protected from physical stress, antimicrobials, and the host immune system, and thereby cause severe medical, environmental, and technical problems. Biofilm formatio...

General protein information

Preferred Names
partially deacetylated poly-beta-1,6-N-acetyl-D-glucosamine outer membrane porin

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1089866..1092289 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415543.1 partially deacetylated poly-beta-1,6-N-acetyl-D-glucosamine outer membrane porin [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415543.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P69434
    Conserved Domains (2) summary
    PRK10049
    Location:53807
    pgaA; outer membrane protein PgaA; Provisional
    sd00006
    Location:98126
    TPR; TPR repeat [structural motif]
Support Center