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pgaA partially deacetylated poly-beta-1,6-N-acetyl-D-glucosamine outer membrane porin [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945596, updated on 10-Oct-2019

Summary

Gene symbol
pgaA
Gene description
partially deacetylated poly-beta-1,6-N-acetyl-D-glucosamine outer membrane porin
Primary source
EcoGene:EG13865
Locus tag
b1024
See related
ASAP:ABE-0003469; ECOCYC:G6531
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1014; hmsH; ycdS
Summary
PgaA is homolgous to Y. pestis hemin storage protein HmsH, but is unable to complement hmsH mutations. [More information is available at EcoGene: EG13865]. The pgaABCD locus is required for the synthesis of a cell-bound hexosamine-rich polysaccharide, which was identified as a linear polymer of beta-1,6-N-acetylglucosamine residues (PGA), an adhesin essential in biofilm formation . [More information is available at EcoCyc: G6531].

Genomic context

Sequence:
NC_000913.3 (1089866..1092289, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene poly-N-acetyl-D-glucosamine synthase subunit PgaD Neighboring gene poly-N-acetyl-D-glucosamine synthase subunit PgaC Neighboring gene poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase and beta-1,6 glycoside hydrolase Neighboring gene putative diguanylate cyclase DgcT Neighboring gene IS3 element protein InsF Neighboring gene IS3 element protein InsE

General gene information

Gene Ontology Provided by GO

Process Evidence Code Pubs
biofilm formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
polysaccharide transport IDA
Inferred from Direct Assay
more info
PubMed 
polysaccharide transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell outer membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of cell outer membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
partially deacetylated poly-beta-1,6-N-acetyl-D-glucosamine outer membrane porin

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1089866..1092289 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415543.1 partially deacetylated poly-beta-1,6-N-acetyl-D-glucosamine outer membrane porin [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415543.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P69434
    Conserved Domains (2) summary
    PRK10049
    Location:53807
    pgaA; outer membrane protein PgaA; Provisional
    sd00006
    Location:98126
    TPR; TPR repeat [structural motif]
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