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gfcE putative exopolysaccharide export lipoprotein GfcE [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945586, updated on 11-Apr-2024

Summary

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Gene symbol
gfcE
Gene description
putative exopolysaccharide export lipoprotein GfcE
Primary source
ASAP:ABE-0003317
Locus tag
b0983
See related
ECOCYC:G6504
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0974; yccZ
Summary
GfcE may form a channel through the outer membrane for transport of the O-antigen capsule polysaccharides. yccZ and wza are paralogs. [More information is available at EcoGene: EG13728]. The operon encoding YmcD, YmcC, YmcB, YmcA, YzzZ, Etp, and Etk was characterized in the enteropathogenic Escherichia coli strain O127:H6. [More information is available at EcoCyc: G6504].
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Genomic context

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Sequence:
NC_000913.3 (1044664..1045803, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene periplasmic phosphoanhydride phosphatase/multiple inositol-polyphosphate phosphatase Neighboring gene protein-tyrosine kinase Etk Neighboring gene phosphotyrosine-protein phosphatase Etp Neighboring gene putative lipoprotein GfcD Neighboring gene capsule biosynthesis GfcC family protein Neighboring gene lipoprotein GfcB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. PELDOR spectroscopy distance fingerprinting of the octameric outer-membrane protein Wza from Escherichia coli. Hagelueken G, et al. Angew Chem Int Ed Engl, 2009. PMID 19294709, Free PMC Article
  2. Wza the translocon for E. coli capsular polysaccharides defines a new class of membrane protein. Dong C, et al. Nature, 2006 Nov 9. PMID 17086202, Free PMC Article
  3. Computer-based analyses of the protein constituents of transport systems catalysing export of complex carbohydrates in bacteria. Paulsen IT, et al. Microbiology (Reading), 1997 Aug. PMID 9274022
  4. Biosynthesis and assembly of capsular polysaccharides in Escherichia coli. Whitfield C. Annu Rev Biochem, 2006. PMID 16756484
  5. BOMP: a program to predict integral beta-barrel outer membrane proteins encoded within genomes of Gram-negative bacteria. Berven FS, et al. Nucleic Acids Res, 2004 Jul 1. PMID 15215418, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables polysaccharide transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables porin activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in organic substance transport IEA
Inferred from Electronic Annotation
more info
  
involved_in polysaccharide transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of pore complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
putative exopolysaccharide export lipoprotein GfcE

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1044664..1045803 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415503.1 putative exopolysaccharide export lipoprotein GfcE [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415503.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9A8U2, A0A8T5YK45
    Conserved Domains (1) summary
    PRK15078
    Location:1 → 377
    PRK15078; polysaccharide export protein Wza; Provisional
Nucleotide Protein
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