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hspQ heat shock protein HspQ [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945578, updated on 3-Dec-2024
Official Symbol
hspQ
Official Full Name
heat shock protein HspQ
Primary source
ECOCYC:G6500
Locus tag
b0966
See related
ASAP:ABE-0003269
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0957; yccV
Summary
A mutation in hspQ allows some dnaA(Ts) strains to grow at 40C, and slows the degradation of DnaA508 at 40C. [More information is available at EcoGene: EG13724]. HspQ binds to hemimethylated DNA at oriC . [More information is available at EcoCyc: G6500].
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Sequence:
NC_000913.3 (1028404..1028721, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DUF2057 domain-containing protein YccT Neighboring gene putative HspQ acetyl donor Neighboring gene 23S rRNA m(5)C1962 methyltransferase Neighboring gene acylphosphatase Neighboring gene sulfur transfer protein TusE

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. X-ray crystal structure of Escherichia coli HspQ, a protein involved in the retardation of replication initiation. Abe Y, et al. FEBS Lett, 2017 Nov. PMID 29083032
  2. The global transcriptional response of Escherichia coli to induced sigma 32 protein involves sigma 32 regulon activation followed by inactivation and degradation of sigma 32 in vivo. Zhao K, et al. J Biol Chem, 2005 May 6. PMID 15757896
  3. Regulon and promoter analysis of the E. coli heat-shock factor, sigma32, reveals a multifaceted cellular response to heat stress. Nonaka G, et al. Genes Dev, 2006 Jul 1. PMID 16818608, Free PMC Article
  4. Novel heat shock protein HspQ stimulates the degradation of mutant DnaA protein in Escherichia coli. Shimuta TR, et al. Genes Cells, 2004 Dec. PMID 15569148
  5. Isolation of a new hemimethylated DNA binding protein which regulates dnaA gene expression. d'Alençon E, et al. J Bacteriol, 2003 May. PMID 12700277, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on complete protein
    Title: Novel heat shock protein HspQ stimulates the degradation of mutant DnaA protein in Escherichia coli.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables hemi-methylated DNA-binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within protein homotrimerization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in response to heat IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
heat shock protein HspQ

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1028404..1028721 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415486.4 heat shock protein HspQ [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415486.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A484WQQ4
    Conserved Domains (1) summary
    PRK14129
    Location:1 → 105
    PRK14129; heat shock protein HspQ; Provisional
Nucleotide Protein
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