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cmoM tRNA cmo(5)U34 methyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945547, updated on 30-Jul-2025
Official Symbol
cmoM
Official Full Name
tRNA cmo(5)U34 methyltransferase
Primary source
ECOCYC:EG12167
Locus tag
b0921
See related
ASAP:ABE-0003131
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0912; smtA; ycbD
Summary
SmtA shows sequence similarity to SAM-dependent methyltransferases . [More information is available at EcoCyc: EG12167].
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Sequence:
NC_000913.3 (973537..974322)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene PF03966 family protein YcaR Neighboring gene 3-deoxy-manno-octulosonate cytidylyltransferase Neighboring gene putative phosphotransferase YcbJ Neighboring gene envelope biogenesis factor Neighboring gene chromosome partitioning protein MukF Neighboring gene chromosome partitioning protein MukE Neighboring gene chromosome partitioning protein MukB Neighboring gene L,D-transpeptidase LdtD

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Biogenesis and growth phase-dependent alteration of 5-methoxycarbonylmethoxyuridine in tRNA anticodons. Sakai Y, et al. Nucleic Acids Res, 2016 Jan 29. PMID 26681692, Free PMC Article
  2. Identification of two new genes, mukE and mukF, involved in chromosome partitioning in Escherichia coli. Yamanaka K, et al. Mol Gen Genet, 1996 Feb 25. PMID 8602138
  3. Characterization of the smtA gene encoding an S-adenosylmethionine-dependent methyltransferase of Escherichia coli. Yamanaka K, et al. FEMS Microbiol Lett, 1995 Nov 1. PMID 8566713
  4. New killing system controlled by two genes located immediately upstream of the mukB gene in Escherichia coli. Feng J, et al. Mol Gen Genet, 1994 Apr. PMID 7513784
  5. RecA-dependent mutants in Escherichia coli reveal strategies to avoid chromosomal fragmentation. Kouzminova EA, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15531636, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables tRNA (5-carboxymethoxyuridine(34)-5-O)-methyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables tRNA (5-carboxymethoxyuridine(34)-5-O)-methyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in methylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within tRNA methylation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in tRNA modification IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA processing IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within tRNA wobble uridine modification IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Preferred Names
tRNA cmo(5)U34 methyltransferase

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    973537..974322
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415441.1 tRNA cmo(5)U34 methyltransferase

    See identical proteins and their annotated locations for NP_415441.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A5B9ANN0
    Conserved Domains (1) summary
    PRK11036
    Location:1 → 255
    PRK11036; tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM
Nucleotide Protein
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