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infA translation initiation factor IF-1 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945500, updated on 6-May-2021

Summary

Gene symbol
infA
Gene description
translation initiation factor IF-1
Primary source
ASAP:ABE-0003005
Locus tag
b0884
See related
ECOCYC:EG10504
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
bypA1; ECK0875
Summary
INfA acts as transcription antiterminator and has RNA chaperone activity in vivo and in vitro (Phadtare, 2007). [More information is available at EcoGene: EG10504]. IF-1 is one of three translation initiation factors in Escherichia coli and is essential for viability . [More information is available at EcoCyc: EG10504].
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Genomic context

Sequence:
NC_000913.3 (926225..926443, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ATP-dependent Clp protease ATP-binding subunit ClpA Neighboring gene tRNA Neighboring gene leucyl/phenylalanyl-tRNA--protein transferase Neighboring gene glutathione/L-cysteine ABC exporter subunit CydC

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
 
enables ribosome binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables ribosome binding IDA
Inferred from Direct Assay
more info
PubMed 
enables ribosome binding IEA
Inferred from Electronic Annotation
more info
 
enables translation initiation factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within translational initiation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
translation initiation factor IF-1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    926225..926443 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415404.1 translation initiation factor IF-1 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415404.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P69222
    Conserved Domains (1) summary
    PRK00276
    Location:172
    infA; translation initiation factor IF-1; Validated
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