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grxA reduced glutaredoxin 1 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945479, updated on 8-Dec-2022

Summary

Gene symbol
grxA
Gene description
reduced glutaredoxin 1
Primary source
ASAP:ABE-0002893
Locus tag
b0849
See related
ECOCYC:EG10417
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0840; grx
Summary
Glutaredoxins are ubiquitous proteins that catalyze the reduction of disulfides via reduced glutathione (GSH). [More information is available at EcoCyc: EG10417].
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Genomic context

Sequence:
NC_000913.3 (890496..890753, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transport protein YbjL Neighboring gene putative inner membrane protein Neighboring gene DUF1418 domain-containing protein YbjC Neighboring gene NADPH-dependent nitro/quinone reductase NfsA Neighboring gene ribosomal protein S6 modification protein

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables disulfide oxidoreductase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables electron transfer activity IEA
Inferred from Electronic Annotation
more info
 
enables glutathione disulfide oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein-disulfide reductase (glutathione) activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein-disulfide reductase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein-disulfide reductase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
reduced glutaredoxin 1
NP_415370.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    890496..890753 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415370.1 reduced glutaredoxin 1 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415370.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P68688
    Conserved Domains (1) summary
    PRK11200
    Location:184
    grxA; glutaredoxin 1; Provisional