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gsiB glutathione ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945459, updated on 25-Jan-2024

Summary

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Gene symbol
gsiB
Gene description
glutathione ABC transporter periplasmic binding protein
Primary source
ASAP:ABE-0002832
Locus tag
b0830
See related
ECOCYC:G6430
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0820; yliB
Summary
The first 26 aa are predicted to be a signal peptide. [More information is available at EcoGene: EG13473]. [More information is available at EcoCyc: G6430].
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Genomic context

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Sequence:
NC_000913.3 (869411..870949)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene molybdopterin-synthase adenylyltransferase Neighboring gene molybdopterin molybdotransferase Neighboring gene isoaspartyl dipeptidase proenzyme Neighboring gene glutathione ABC transporter ATP binding subunit GsiA Neighboring gene glutathione ABC transporter membrane subunit GsiC Neighboring gene glutathione ABC transporter membrane subunit GsiD

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. [Cloning and optimizing expression of a periplasmic solute-binding gene gsiB from Escherichia coli]. Wang ZS, et al. Yi Chuan, 2010 May. PMID 20466641
  2. The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette. Suzuki H, et al. J Bacteriol, 2005 Sep. PMID 16109926, Free PMC Article
  3. Purification and Characterization of Glutathione Binding Protein GsiB from Escherichia coli. Wang Z, et al. Biomed Res Int, 2018. PMID 30515393, Free PMC Article
  4. Comparison of the large-scale periplasmic proteomes of the Escherichia coli K-12 and B strains. Han MJ, et al. J Biosci Bioeng, 2014 Apr. PMID 24140104
  5. Enrichment of low abundance proteins of Escherichia coli by hydroxyapatite chromatography. Fountoulakis M, et al. Electrophoresis, 1999 Aug. PMID 10493123

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. GsiB functions in E. coli was characterized which could help elucidate the glutathione import mechanism in gram-negative bacteria
    Title: Purification and Characterization of Glutathione Binding Protein GsiB from Escherichia coli.
  2. Stduies show that the cloned coding sequence of gsiB that encodes the periplasmic solute-binding protein of a glutathione transporter was amplified by PCR, and then inserted into a prokaryotic expression vector pWaldo-GFP.
    Title: [Cloning and optimizing expression of a periplasmic solute-binding gene gsiB from Escherichia coli].
  3. Imports extracellular glutathione into the cytoplasm in an ATP-dependent manner.
    Title: The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables peptide transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in dipeptide transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex IEA
Inferred from Electronic Annotation
more info
  
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in outer membrane-bounded periplasmic space IEA
Inferred from Electronic Annotation
more info
  
located_in outer membrane-bounded periplasmic space RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glutathione ABC transporter periplasmic binding protein
NP_415351.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    869411..870949
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415351.1 glutathione ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415351.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7JXJ2
    Conserved Domains (1) summary
    PRK15413
    Location:1 → 512
    PRK15413; glutathione ABC transporter substrate-binding protein GsiB; Provisional
Nucleotide Protein
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