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deoR DNA-binding transcriptional repressor DeoR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945453, updated on 19-Feb-2025
Official Symbol
deoR
Official Full Name
DNA-binding transcriptional repressor DeoR
Primary source
ECOCYC:EG10223
Locus tag
b0840
See related
ASAP:ABE-0002862
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0830; nucR
Summary
DeoR is a DNA-binding transcriptional regulator that is involved in the negative regulation of genes that encode nucleotide catabolism (deoCABD, nupG, and tsx). [More information is available at EcoCyc: EG10223].
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Sequence:
NC_000913.3 (881976..882734, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene aldose sugar dehydrogenase YliI Neighboring gene glutathione S-transferase GstB Neighboring gene D-alanyl-D-alanine carboxypeptidase DacC Neighboring gene undecaprenyl pyrophosphate phosphatase Neighboring gene multidrug efflux pump MdfA/Na(+):H(+) antiporter/K(+):H(+) antiporter

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Design, synthesis, biological evaluation and pharmacokinetics of bis(hydroxyphenyl) substituted azoles, thiophenes, benzenes, and aza-benzenes as potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1). Bey E, et al. J Med Chem, 2008 Nov 13. PMID 18855374
  2. Multiple regulation of nucleoside catabolizing enzymes: regulation of the deo operon by the cytR and deoR gene products. Hammer-Jespersen K, et al. Mol Gen Genet, 1975. PMID 171553
  3. DeoR repression at-a-distance only weakly responds to changes in interoperator separation and DNA topology. Dandanell G. Nucleic Acids Res, 1992 Oct 25. PMID 1437558, Free PMC Article
  4. The structure of tandem regulatory regions in the deo operon of Escherichia coli K12. Valentin-Hansen P, et al. EMBO J, 1982. PMID 16453417, Free PMC Article
  5. Long-distance deoR regulation of gene expression in Escherichia coli. Dandanell G, et al. Ann N Y Acad Sci, 1991 Dec 27. PMID 1809188

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables cis-regulatory region sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables ligand-modulated transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of DNA-templated transcription initiation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
DNA-binding transcriptional repressor DeoR

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    881976..882734 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415361.1 DNA-binding transcriptional repressor DeoR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415361.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7A6JM63
    Conserved Domains (1) summary
    PRK10681
    Location:1 → 252
    PRK10681; DNA-binding transcriptional repressor DeoR; Provisional
Nucleotide Protein
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