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ybjG undecaprenyl pyrophosphate phosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945450, updated on 26-Mar-2025
Official Symbol
ybjG
Official Full Name
undecaprenyl pyrophosphate phosphatase
Primary source
ECOCYC:G6439
Locus tag
b0841
See related
ASAP:ABE-0002865
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0831
Summary
The ybjG gene is not essential, but UppP activity is essential to synthesize undecaprenyl phosphate, a C55 lipid carrier for cell wall synthesis, so a ybjG pgpB bacA triple mutant is lethal; overexpression, but not wildtype levels, of the LpxT(YeiU) UppP activity rescues the triple mutant (El Ghachi, 2005). [More information is available at EcoGene: EG13676]. YbjG is similar to a bacitracin resistance protein BcrC of Bacillus licheniformis. [More information is available at EcoCyc: G6439].
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Sequence:
NC_000913.3 (882792..883388, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene D-alanyl-D-alanine carboxypeptidase DacC Neighboring gene DNA-binding transcriptional repressor DeoR Neighboring gene multidrug efflux pump MdfA/Na(+):H(+) antiporter/K(+):H(+) antiporter Neighboring gene uncharacterized protein YbjH

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Resistance to bacitracin as modulated by an Escherichia coli homologue of the bacitracin ABC transporter BcrC subunit from Bacillus licheniformis. Harel YM, et al. J Bacteriol, 1999 Oct. PMID 10498733, Free PMC Article
  2. Periplasmic phosphorylation of lipid A is linked to the synthesis of undecaprenyl phosphate. Touzé T, et al. Mol Microbiol, 2008 Jan. PMID 18047581, Free PMC Article
  3. An Escherichia coli undecaprenyl-pyrophosphate phosphatase implicated in undecaprenyl phosphate recycling. Tatar LD, et al. Microbiology (Reading), 2007 Aug. PMID 17660416
  4. Unique stress response to the lactoperoxidase-thiocyanate enzyme system in Escherichia coli. Sermon J, et al. Res Microbiol, 2005 Mar. PMID 15748988
  5. Signal transduction cascade between EvgA/EvgS and PhoP/PhoQ two-component systems of Escherichia coli. Eguchi Y, et al. J Bacteriol, 2004 May. PMID 15126461, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables undecaprenyl-diphosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables undecaprenyl-diphosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
  
involved_in peptidoglycan biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
  
involved_in response to antibiotic IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to antibiotic IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
undecaprenyl pyrophosphate phosphatase
NP_415362.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    882792..883388 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415362.1 undecaprenyl pyrophosphate phosphatase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415362.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    H9DVC7
    Conserved Domains (1) summary
    PRK11837
    Location:1 → 198
    PRK11837; undecaprenyl pyrophosphate phosphatase; Provisional
Nucleotide Protein
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