U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ybjG undecaprenyl pyrophosphate phosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945450, updated on 22-Sep-2022

Summary

Gene symbol
ybjG
Gene description
undecaprenyl pyrophosphate phosphatase
Primary source
ASAP:ABE-0002865
Locus tag
b0841
See related
ECOCYC:G6439
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0831
Summary
The ybjG gene is not essential, but UppP activity is essential to synthesize undecaprenyl phosphate, a C55 lipid carrier for cell wall synthesis, so a ybjG pgpB bacA triple mutant is lethal; overexpression, but not wildtype levels, of the LpxT(YeiU) UppP activity rescues the triple mutant (El Ghachi, 2005). [More information is available at EcoGene: EG13676]. YbjG is similar to a bacitracin resistance protein BcrC of Bacillus licheniformis. [More information is available at EcoCyc: G6439].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Sequence:
NC_000913.3 (882792..883388, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene D-alanyl-D-alanine carboxypeptidase DacC Neighboring gene DNA-binding transcriptional repressor DeoR Neighboring gene multidrug efflux pump MdfA/Na(+):H(+) antiporter/K(+):H(+) antiporter Neighboring gene uncharacterized protein YbjH

Pathways from PubChem

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables undecaprenyl-diphosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables undecaprenyl-diphosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
 
involved_in peptidoglycan biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 
involved_in response to antibiotic IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within response to antibiotic IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
undecaprenyl pyrophosphate phosphatase
NP_415362.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    882792..883388 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415362.1 undecaprenyl pyrophosphate phosphatase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415362.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P75806
    Conserved Domains (1) summary
    PRK11837
    Location:1198
    PRK11837; undecaprenyl pyrophosphate phosphatase; Provisional