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mntR DNA-binding transcriptional dual regulator MntR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945437, updated on 30-Jul-2025
Official Symbol
mntR
Official Full Name
DNA-binding transcriptional dual regulator MntR
Primary source
ECOCYC:G6420
Locus tag
b0817
See related
ASAP:ABE-0002793
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0807; ybiQ
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Sequence:
NC_000913.3 (853183..853650)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene phosphoethanolamine transferase OpgE Neighboring gene ncRNA Neighboring gene small protein MntS Neighboring gene putative transporter YbiR Neighboring gene L,D-transpeptidase LdtB Neighboring gene putative ATP-binding protein YbiT

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Crystal structure of the manganese transport regulatory protein from Escherichia coli. Tanaka T, et al. Proteins, 2009 Nov 15. PMID 19701940
  2. The Escherichia coli K-12 MntR miniregulon includes dps, which encodes the major stationary-phase DNA-binding protein. Yamamoto K, et al. J Bacteriol, 2011 Mar. PMID 21239586, Free PMC Article
  3. Regulation of Salmonella enterica serovar Typhimurium mntH transcription by H(2)O(2), Fe(2+), and Mn(2+). Kehres DG, et al. J Bacteriol, 2002 Jun. PMID 12029030, Free PMC Article
  4. Dual repression by Fe(2+)-Fur and Mn(2+)-MntR of the mntH gene, encoding an NRAMP-like Mn(2+) transporter in Escherichia coli. Patzer SI, et al. J Bacteriol, 2001 Aug. PMID 11466284, Free PMC Article
  5. Emerging themes in manganese transport, biochemistry and pathogenesis in bacteria. Kehres DG, et al. FEMS Microbiol Rev, 2003 Jun. PMID 12829271

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This work defines two MntR-regulated new proteins, MntS and MntP, involved in manganese homeostasis and suggests mechanisms for their action.
    Title: The Escherichia coli MntR miniregulon includes genes encoding a small protein and an efflux pump required for manganese homeostasis.
  2. Unexpectedly, the authors found that dps expression is directly repressed by Mn(2+)-MntR.
    Title: The Escherichia coli K-12 MntR miniregulon includes dps, which encodes the major stationary-phase DNA-binding protein.
  3. Crystal structure of the manganese transport regulatory protein from Escherichia coli
    Title: Crystal structure of the manganese transport regulatory protein from Escherichia coli.
Submit: New GeneRIF Correction
Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
  
enables transition metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within positive regulation of DNA-templated transcription initiation IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
DNA-binding transcriptional dual regulator MntR

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    853183..853650
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415338.1 DNA-binding transcriptional dual regulator MntR

    See identical proteins and their annotated locations for NP_415338.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A8T6BJK3
    Conserved Domains (1) summary
    PRK11050
    Location:4 → 155
    PRK11050; manganese-binding transcriptional regulator MntR
Nucleotide Protein
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