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moaB protein MoaB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945396, updated on 26-Mar-2025

Summary

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Official Symbol
moaB
Official Full Name
protein MoaB
Primary source
ECOCYC:EG11596
Locus tag
b0782
See related
ASAP:ABE-0002671
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
chlA2; ECK0771
Summary
HT_Cmplx43_Mem: [More information is available at EcoGene: EG11596]. Molybdenum and tungsten cofactors of all enzymes that require one or the other for activity are present in an oxidized state as molybdate or tungstate ions that are chelated by the cis-dithiolene moiety of a molybdenum cofactor. [More information is available at EcoCyc: EG11596].
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Genomic context

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Sequence:
NC_000913.3 (818055..818567)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transferase YbhK Neighboring gene GTP 3',8'-cyclase Neighboring gene cyclic pyranopterin monophosphate synthase Neighboring gene molybdopterin synthase sulfur carrier subunit Neighboring gene molybdopterin synthase catalytic subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic characterization of moaB mutants of Escherichia coli. Kozmin SG, et al. Res Microbiol, 2013 Sep. PMID 23680484, Free PMC Article
  2. Rearrangement reactions in the biosynthesis of molybdopterin--an NMR study with multiply 13C/15N labelled precursors. Rieder C, et al. Eur J Biochem, 1998 Jul 1. PMID 9692897
  3. Molecular genetic analysis of the moa operon of Escherichia coli K-12 required for molybdenum cofactor biosynthesis. Rivers SL, et al. Mol Microbiol, 1993 Jun. PMID 8361352
  4. Characterization of the ModE DNA-binding sites in the control regions of modABCD and moaABCDE of Escherichia coli. McNicholas PM, et al. Mol Microbiol, 1997 Feb. PMID 9044285
  5. Proposed nomenclature for the genes involved in molybdenum metabolism in Escherichia coli and Salmonella typhimurium. Shanmugam KT, et al. Mol Microbiol, 1992 Nov. PMID 1484496

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Transposon insertions in moaB caused partial molybdenum cofactor deficiency associated with chlorate-resistance but not for 6-N-hydroxylaminopurine sensitivity.
    Title: Genetic characterization of moaB mutants of Escherichia coli.
  2. N-terminus verified by Edman degradation on mature peptide
    Title: Molecular genetic analysis of the moa operon of Escherichia coli K-12 required for molybdenum cofactor biosynthesis.
  3. X-ray crystallography of MoaB protein from Escherichia coli
    Title: Structure of the molybdenum-cofactor biosynthesis protein MoaB of Escherichia coli.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in Mo-molybdopterin cofactor biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein hexamerization IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
protein MoaB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    818055..818567
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415303.1 protein MoaB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415303.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A418GNS9
    Conserved Domains (1) summary
    TIGR02667
    Location:7 → 169
    moaB_proteo; molybdenum cofactor biosynthesis protein B, proteobacterial
Nucleotide Protein
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