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mngR DNA-binding transcriptional repressor MngR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945371, updated on 10-Oct-2019

Summary

Gene symbol
mngR
Gene description
DNA-binding transcriptional repressor MngR
Primary source
EcoGene:EG11109
Locus tag
b0730
See related
ASAP:ABE-0002487; ECOCYC:EG11109
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0718; farR; ybgB
Summary
Originally identifed as a fatty acyl-responsive regulator FarR based on in vitro experiments; this conclusion is now in doubt based on microarray experiments. [More information is available at EcoGene: EG11109]. According to microarray analysis, the "mannosyl-d-glycerate regulator," MngR, regulates only two genes, mngA and mngB, involved in 2-O--mannosyl-d-glycerate utilization . [More information is available at EcoCyc: EG11109].

Genomic context

Sequence:
NC_000913.3 (765153..765875, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene succinyl-CoA synthetase subunit beta Neighboring gene succinyl-CoA synthetase subunit alpha Neighboring gene 2-O-alpha-mannosyl-D-glycerate specific PTS enzyme II Neighboring gene alpha-mannosidase

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
negative regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
response to heat IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
DNA-binding transcriptional repressor MngR

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    765153..765875 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415258.1 DNA-binding transcriptional repressor MngR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415258.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P13669
    Conserved Domains (1) summary
    PRK09764
    Location:1240
    PRK09764; DNA-binding transcriptional repressor MngR; Provisional
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