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mngR DNA-binding transcriptional repressor MngR [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 945371, updated on 11-Oct-2018

Summary

Gene symbol
mngR
Gene description
DNA-binding transcriptional repressor MngR
Primary source
EcoGene:EG11109
Locus tag
b0730
See related
ASAP:ABE-0002487; ECOCYC:EG11109
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0718; farR; ybgB
Summary
Originally identifed as a fatty acyl-responsive regulator FarR based on in vitro experiments; this conclusion is now in doubt based on microarray experiments. [More information is available at EcoGene: EG11109]. According to microarray analysis, the "mannosyl-d-glycerate regulator," MngR, regulates only two genes, mngA and mngB, involved in 2-O--mannosyl-d-glycerate utilization . [More information is available at EcoCyc: EG11109].

Genomic context

Sequence:
NC_000913.3 (765153..765875, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene succinyl-CoA synthetase subunit beta Neighboring gene succinyl-CoA synthetase subunit alpha Neighboring gene 2-O-alpha-mannosyl-D-glycerate specific PTS enzyme II Neighboring gene alpha-mannosidase

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
DNA-binding transcription factor activity IDA
Inferred from Direct Assay
more info
PubMed 
DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Process Evidence Code Pubs
negative regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription, DNA-templated IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
response to heat IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
DNA-binding transcriptional repressor MngR

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    765153..765875 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415258.1 DNA-binding transcriptional repressor MngR [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415258.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P13669
    Conserved Domains (1) summary
    PRK09764
    Location:1240
    PRK09764; DNA-binding transcriptional repressor MngR; Provisional
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